Evidence map›Paper›PMID 28268246›Full record

ArticleBrain pathology (Zurich, Switzerland)2018

Cerebellar compartmentation of prion pathogenesis.

Audrey Ragagnin, Juliette Ezpeleta, Aurélie Guillemain, François Boudet-Devaud, Anne-Marie Haeberlé, Valérie Demais, Catherine Vidal, Stanislas Demuth, Vincent Béringue, Odile Kellermann and 3 more

Open access · greenAbstract read
In one paragraph

Article in Brain pathology (Zurich, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. New Light on Prions: Putative Role of PrPInternational journal of molecular sciences · 2024
    Review
  3. The fidelity of transcription in human cells.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Sphingolipid metabolism governs Purkinje cell patterned degeneration inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  5. A 3D cell culture approach for studying neuroinflammation.Journal of neuroscience methods · 2021
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Recent advances on the molecular pathogenesis of prion diseases.Brain pathology (Zurich, Switzerland) · 2019
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Audrey RagagninCytologie et Cytopathologie Neuronales, Institut des Neurosciences Cellulaires & Intégratives, CNRS UPR 3212, Strasbourg, France.
Juliette EzpeletaINSERM UMR-S1124, Cellules Souches, Signalisation et Prions, Université Paris Descartes, Paris, France.
Aurélie GuillemainCytologie et Cytopathologie Neuronales, Institut des Neurosciences Cellulaires & Intégratives, CNRS UPR 3212, Strasbourg, France.
François Boudet-DevaudINSERM UMR-S1124, Cellules Souches, Signalisation et Prions, Université Paris Descartes, Paris, France.
Anne-Marie HaeberléCytologie et Cytopathologie Neuronales, Institut des Neurosciences Cellulaires & Intégratives, CNRS UPR 3212, Strasbourg, France.
Valérie DemaisPlateforme Imagerie In Vitro, CNRS UPS-3156, Université de Strasbourg, Strasbourg, France.
Catherine VidalInstitut Pasteur, Paris, France.
Stanislas DemuthCytologie et Cytopathologie Neuronales, Institut des Neurosciences Cellulaires & Intégratives, CNRS UPR 3212, Strasbourg, France.
Vincent BéringueVIM, INRA, Université Paris-Saclay, Jouy-en-Josas, France.
Odile KellermannINSERM UMR-S1124, Cellules Souches, Signalisation et Prions, Université Paris Descartes, Paris, France.
Benoit SchneiderINSERM UMR-S1124, Cellules Souches, Signalisation et Prions, Université Paris Descartes, Paris, France.
Nancy J GrantCytologie et Cytopathologie Neuronales, Institut des Neurosciences Cellulaires & Intégratives, CNRS UPR 3212, Strasbourg, France.
Yannick BaillyCytologie et Cytopathologie Neuronales, Institut des Neurosciences Cellulaires & Intégratives, CNRS UPR 3212, Strasbourg, France.ORCID 0000-0002-2635-6385
Centre National de la Recherche Scientifique · FRInserm · FRInstitut Pasteur · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In prion diseases, the brain lesion profile is influenced by the prion "strain" properties, the invasion route to the brain, and still unknown host cell-specific parameters. To gain insight into those endogenous factors, we analyzed the histopathological alterations induced by distinct prion strains in the mouse cerebellum. We show that 22L and ME7 scrapie prion proteins (PrP

Indexed as

AnimalsAstrocytesCattleCerebellumEncephalopathy, Bovine SpongiformExcitatory Amino Acid Transporter 4Green Fluorescent ProteinsInflammationMice, Inbred C57BLMice, TransgenicMicrogliaNeuronsPrion ProteinsReceptors, Tumor Necrosis Factor, Type IScrapieSynapsesenhanced green fluorescent proteinExcitatory Amino Acid Transporter 4Green Fluorescent ProteinsPrion ProteinsReceptors, Tumor Necrosis Factor, Type ISlc1a6 protein, mouseTnfrsf1a protein, mousecerebellar compartmentationinflammationprionPurkinje cellzebrin

Identifiers

PMID28268246
PMCPMC8028594
OpenAlexW2592015659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.