Evidence map›Paper›PMID 28267808›Full record

SynthesisPloS one2017

Gastric-tube versus whole-stomach esophagectomy for esophageal cancer: A systematic review and meta-analysis.

Wenxiong Zhang, Dongliang Yu, Jinhua Peng, Jianjun Xu, Yiping Wei

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04107623 (Quantitative Fluorescent Guided Robotic Surgery for Cancer of the Gastroesophageal Junction), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04107623 nacompletednot on this mapstarted 2020, after this paper: background citation

Quantitative Fluorescent Guided Robotic Surgery for Cancer of the Gastroesophageal Junction

TypeinterventionalSponsorRigshospitalet, DenmarkRan2020 to 2021Enrolled70ConditionsStomach Neoplasms, SurgeryArmsIndocyanine Green
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Delayed gastric conduit emptying after esophagectomy: attempt at a clinically relevant classification.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Comparison of wide and narrow gastric conduit in esophageal cancer surgery.Journal of the Chinese Medical Association : JCMA · 2023
    Article
  8. Article
  9. Article
  10. Different gastric tubes in esophageal reconstruction during esophagectomy.Esophagus : official journal of the Japan Esophageal Society · 2023
    Review
  11. Review
  12. Wider Gastric Conduit Morphology Is Associated with Improved Blood Flow During Esophagectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Delayed Gastric Emptying after Esophagectomy: Management and Prevention.The Korean journal of thoracic and cardiovascular surgery · 2020
    Article
  20. Reflux Following Esophagectomy for Esophageal Cancer.The Korean journal of thoracic and cardiovascular surgery · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wenxiong ZhangDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Dongliang YuDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jinhua PengDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jianjun XuDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Yiping WeiDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNSecond Affiliated Hospital of Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo conduct a systematic review and meta-analysis of studies comparing the gastric-tube vs. whole-stomach for esophageal cancer in order to determine the optimal surgical technique of esophagectomy.

methodsA comprehensive literature search was performed using PubMed, EMBASE, ScienceDirect, Ovid MEDLINE, Cochrane Library, Web of Science, Google Scholar, and Scopus. Clinical trials that compared the gastric-tube versus whole-stomach for esophageal cancer were selected. The clinical endpoints included anastomotic leakage, anastomotic stenosis, reflux esophagitis, pneumonia, delayed gastric emptying, and thoracic stomach syndrome.

resultsA total of 6 articles (1571 patients) were included. Compared to the whole-stomach approach, the gastric-tube approach was associated with a lower incidence of reflux esophagitis (95% confidence interval [CI]: 0.16 to 0.81, p = 0.01) and thoracic stomach syndrome (95% CI: 0.17 to 0.55, p < 0.0001). The rates of anastomotic leakage, anastomotic stenosis, pneumonia, and delayed gastric emptying did not significantly differ between the two groups.

conclusionsThe gastric-tube esophagectomy is superior to the whole-stomach approach, as it is associated with a lower incidence of postoperative reflux esophagitis and thoracic stomach syndrome. Our findings must be validated in large-scale randomized controlled trials.

Indexed as

Anastomotic LeakEsophageal NeoplasmsEsophagectomyEsophagitis, PepticHumansPneumoniaPublication Bias

Identifiers

PMID28267808
PMCPMC5340360
OpenAlexW2593616932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.