ArticleAnnals of the American Thoracic Society2017
Patients with Chronic Obstructive Pulmonary Disease Walk with Altered Step Time and Step Width Variability as Compared with Healthy Control Subjects.
Article in Annals of the American Thoracic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gait differences between COPD and healthy controls: systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Technologies for the Instrumental Evaluation of Physical Function in Persons Affected by Chronic Obstructive Pulmonary Disease: A Systematic Review.Sensors (Basel, Switzerland) · 2022Pooled it
- The Coefficient of Variation of Step Time Can Overestimate Gait Abnormality: Test-Retest Reliability of Gait-Related Parameters Obtained with a Tri-Axial Accelerometer in Healthy Subjects.Sensors (Basel, Switzerland) · 2020Trial
- Criterion Validity of a Consumer Wearable for Step Counting and Activity Intensity Classification in Adults With Lung Cancer: Laboratory-Based Validation Study.JMIR formative research · 2026Article
- Evaluating Changes in Physical Activity and Clinical Outcomes During Post-Hospitalisation Rehabilitation for Persons with COPD: A Prospective Observational Cohort Study.Sensors (Basel, Switzerland) · 2026Observational
- Are Real-World Mobility Patterns Early Indicators of COPD Onset? Insights from Wrist-Worn Sensors.International journal of chronic obstructive pulmonary disease · 2026Article
- How do people with COPD walk? A European study on digitally measured real-world gait.The European respiratory journal · 2025Article
- The Association Between Daily Step Count, Step Frequency and the Risk of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study Using NHANES Data.International journal of chronic obstructive pulmonary disease · 2025Article
- Article
- Comparison between patients with COPD and healthy subjects on spatiotemporal, moment and kinematic parameters: A quasi-experimental study.Health science reports · 2024Article
- Pulmonary and physical function limitations in aging men with and without HIV from the Multicenter AIDS Cohort Study (MACS).Annals of epidemiology · 2022Article
- Locomotor-respiratory coupling in ambulatory adults with incomplete spinal cord injury.Spinal cord series and cases · 2022Observational
- Updated Perspectives on the Role of Biomechanics in COPD: Considerations for the Clinician.International journal of chronic obstructive pulmonary disease · 2022Review
- Factors influencing self-selected walking speed in fibrotic interstitial lung disease.Scientific reports · 2021Observational
- Margin of Stability May Be Larger and Less Variable during Treadmill Walking Versus Overground.Biomechanics (Basel, Switzerland) · 2021Article
- COPD Patients Have a Restricted Breathing Pattern That Persists with Increased Metabolic Demands.COPD · 2020Article
- Subjects With COPD Walk With Less Consistent Organization of Movement Patterns of the Lower Extremity.Respiratory care · 2020Article
- Chronic obstructive pulmonary disease patients increase medio-lateral stability and limit changes in antero-posterior stability to curb energy expenditure.Gait & posture · 2020Article
- Effects of Pulmonary Rehabilitation on Gait Characteristics in Patients with COPD.Journal of clinical medicine · 2019Article
- Energy efficient physiologic coupling of gait and respiration is altered in chronic obstructive pulmonary disease.Acta physiologica (Oxford, England) · 2019Article
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Authors and funding
5 authors.
Funding
Abstract
rationaleCompared with control subjects, patients with chronic obstructive pulmonary disease (COPD) have an increased incidence of falls and demonstrate balance deficits and alterations in mediolateral trunk acceleration while walking. Measures of gait variability have been implicated as indicators of fall risk, fear of falling, and future falls.
objectivesTo investigate whether alterations in gait variability are found in patients with COPD as compared with healthy control subjects.
methodsTwenty patients with COPD (16 males; mean age, 63.6 ± 9.7 yr; FEV
resultsPatients with COPD demonstrated increased mean and SD step time across all speed conditions as compared with control subjects. They also walked with a narrower step width that increased with increasing speed, whereas the healthy control subjects walked with a wider step width that decreased as speed increased. Further, patients with COPD demonstrated less variability in step width, with decreased SD, compared with control subjects at all three speed conditions. No differences in regularity of gait patterns were found between groups.
conclusionsPatients with COPD walk with increased duration of time between steps, and this timing is more variable than that of control subjects. They also walk with a narrower step width in which the variability of the step widths from step to step is decreased. Changes in these parameters have been related to increased risk of falling in aging research. This provides a mechanism that could explain the increased prevalence of falls in patients with COPD.
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