Evidence map›Paper›PMID 28267356›Full record

ArticleAJR. American journal of roentgenology2017

CT of Patients With Hip Fracture: Muscle Size and Attenuation Help Predict Mortality.

Robert D Boutin, Sara Bamrungchart, Cyrus P Bateni, Daniel P Beavers, Kristen M Beavers, John P Meehan, Leon Lenchik

Abstract read
In one paragraph

Article in AJR. American journal of roentgenology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Approaches to Assessment of Muscle Mass and Myosteatosis on Computed Tomography: A Systematic Review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Pooled it
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  7. Automated Muscle Measurement on Chest CT Predicts All-Cause Mortality in Older Adults From the National Lung Screening Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Trial
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  18. Effect of sarcopenia on mortality in acute stroke patients receiving endovascular treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robert D Boutin1 Department of Radiology, University of California Davis School of Medicine, 4860 Y St, Ste 3100, Sacramento, CA 95817.
Sara Bamrungchart1 Department of Radiology, University of California Davis School of Medicine, 4860 Y St, Ste 3100, Sacramento, CA 95817.
Cyrus P Bateni1 Department of Radiology, University of California Davis School of Medicine, 4860 Y St, Ste 3100, Sacramento, CA 95817.
Daniel P Beavers2 Department of Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Kristen M Beavers3 Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC.
John P Meehan4 Department of Orthopaedic Surgery, University of California Davis School of Medicine, Sacramento, CA.
Leon Lenchik5 Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC.

Funding

Effect of Exercise Modality During Weight Loss on Bone Health in Older AdultsK01AG047921 · NIA · WAKE FOREST UNIVERSITY · PI BEAVERS, KRISTEN MARIE · 2015 to 2018
$463k
NIA NIH HHS K01 AG047921
6 · The paper itself

Abstract

objectiveOur objective was to determine the association between muscle cross-sectional area and attenuation, as measured on routine CT scans, and mortality in older patients with hip fracture. MATERIALS AND

methodsA retrospective 10-year study of patients with hip fracture was conducted with the following inclusion criteria: age 65 years or older, first-time hip fracture treated with surgery, and CT of the chest, abdomen, or pelvis. This yielded 274 patients (70.4% women; mean [± SD] age, 81.3 ± 8.3 years). On each CT scan, two readers independently measured the size (cross-sectional area, indexed for patient height) and attenuation of the paravertebral muscle at T12 and the psoas muscle at L4. We then determined the association between overall mortality and the muscle size and muscle attenuation, while adjusting for demographic variables (age, sex, ethnicity, and body mass index), American Society of Anesthesiologists (ASA) classification, and Charlson comorbidity index (CCI).

resultsThe overall mortality rate increased from 28.3% at 1 year to 79.5% at 5 years. Mortality was associated with decreased thoracic muscle size (odds ratio [OR], 0.66; 95% CI, 0.49-0.87). This association persisted after adjusting for demographic variables (OR, 0.69; 95% CI, 0.50-0.95), the ASA classification (OR, 0.70; CI, 0.51-0.97), and the CCI (OR, 0.72; 95% CI, 0.52-1.00). Similarly, decreased survival was associated with decreased thoracic muscle attenuation after adjusting for all of these combinations of covariates (OR, 0.67-0.72; 95% CI, 0.49-0.99). Decreased lumbar muscle size and attenuation trended with decreased survival but did not reach statistical significance.

conclusionIn older adults with hip fractures, CT findings of decreased thoracic paravertebral muscle size and attenuation are associated with decreased overall survival.

Indexed as

Survival AnalysisAged, 80 and overCaliforniaCausalityComorbidityFemaleHip FracturesHumansMaleOrgan SizePrevalenceProportional Hazards ModelsReproducibility of ResultsRetrospective StudiesRisk AssessmentSarcopeniaCThip fracturemortalitymusclesarcopenia

Identifiers

PMID28267356
PMCPMC5898447

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.