Evidence map›Paper›PMID 28266899›Full record

ArticleJournal of psychoactive drugs

The Blue Lotus Flower (Nymphea caerulea) Resin Used in a New Type of Electronic Cigarette, the Re-Buildable Dripping Atomizer.

Justin L Poklis, Haley A Mulder, Matthew S Halquist, Carl E Wolf, Alphonse Poklis, Michelle R Peace

Abstract read
In one paragraph

Article in Journal of psychoactive drugs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Ethyl acetate in e-liquids: Implications for breath testing.Journal of analytical toxicology · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Interpol review of controlled substances 2016-2019.Forensic science international. Synergy · 2020
    Review
  8. Article
  9. Design Features in Multiple Generations of Electronic Cigarette Atomizers.International journal of environmental research and public health · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Justin L Poklisa Science II, Department of Pharmacology and Toxicology , Virginia Commonwealth University , Richmond , VA , USA.ORCID 0000-0001-5470-5717
Haley A Mulderb Graduate Student, Department of Forensic Science , Virginia Commonwealth University , Richmond , VA , USA.
Matthew S Halquistc Assistant Professor, School of Pharmacy , Virginia Commonwealth University , Richmond , VA , USA.
Carl E Wolfd Assistant Professor, Departments of Pathology and Forensic Science , Virginia Commonwealth University , Richmond , VA , USA.
Alphonse Poklise Professor, Departments of Pathology, Pharmacology and Toxicology and Forensic Science , Virginia Commonwealth University , Richmond , VA , USA.
Michelle R Peacef Associate Chair, Department of Forensic Science , Virginia Commonwealth University , Richmond , VA , USA.
Virginia Commonwealth University · US

Funding

VCU Center for Drug Addiction ResearchP30DA033934 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew Sean Halquist · 2014 to 2026
$13.8M
Signal Transduction Mechanism of Osteoclast DifferentiationI01BX000150 · VA · SOUTH TEXAS VETERANS HEALTH CARE SYSTEM · PI GHOSH-CHOUDHURY, NANDINI · 2009 to 2013
–
BLRD VA I01 BX000150NIDA NIH HHS P30 DA033934
6 · The paper itself

Abstract

The blue lotus flower (Nymphea caerulea) is an Egyptian water lily containing apomorphine and nuciferine. Apomorphine has been described as a psychoactive alkaloid and is a non-selective dopamine agonist primarily used to treat Parkinson's disease as it stimulates dopamine receptors and improves motor function. Nuciferine is an alkaloid associated with dopamine receptor blockade. Today, blue lotus flower is used as a sleep aid and anxiety reliever. The rebuildable dripping atomizer (RDA) is an electronic cigarette that allows direct application of an e-liquid onto the coil in the atomizer for aerosolization, compared to a typical electronic cigarette where the e-liquid is wicked from a storage vessel to the coil. Our laboratory received a dark-brown resin material from a concerned parent. The resin had been confiscated from an adolescent who had a reported history of marijuana use. The resin was later identified as blue lotus flower (N. caerulea). This resin, together with four commercially available blue lotus products, was analyzed for content. Apomorphine was detected in two samples, and nuciferine was detected in all five samples. The confiscated resin was determined to contain no apomorphine and 4300 ng/g of nuciferine. The nuciferine resin was shown to aerosolize using aRDA electric cigarette.

Indexed as

Electronic Nicotine Delivery SystemsNebulizers and VaporizersNymphaeaApomorphineAporphinesDopamine AgonistsHumansResins, PlantApomorphineAporphinesDopamine AgonistsnuciferineResins, PlantApomorphineblue lotus flowerelectronic cigarettenuciferine

Identifiers

PMID28266899
PMCPMC5638439
OpenAlexW2592839781

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.