ArticleScientific reports2017
A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Th17/Treg imbalance in patients with severe acute pancreatitis: Attenuated by high-volume hemofiltration treatment.Medicine · 2020Trial
- TRANCE is a unique marker of chronic pancreatitis in children.JCI insight · 2026Article
- A clinical study on the application of new inflammatory markers SII, SIRI, AISI, and MII in the identification of severe acute pancreatitis.Frontiers in medicine · 2026Article
- Changes in inflammatory composite markers and DZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Assessment of early factors for identification or prediction severe acute pancreatitis in pregnancy.World journal of clinical cases · 2024Article
- Predictive power of HALP score in estimating short-term mortality in patients with acute pancreatitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Review
- Expression level of serum miR-374a-5p in patients with acute pancreatitis and its effect on viability, apoptosis, and inflammatory factors of pancreatic acinar cells induced by cerulein.The Kaohsiung journal of medical sciences · 2023Article
- Review
- Accurate prediction of acute pancreatitis severity based on genome-wide cell free DNA methylation profiles.Clinical epigenetics · 2021Article
- T Lymphocytes: A Promising Immunotherapeutic Target for Pancreatitis and Pancreatic Cancer?Frontiers in oncology · 2020Review
- Evaluation of the relationship between the hemoglobin, albumin, lymphocyte, platelet score, and clinical prognosis in patients with acute pancreatitis in the emergency department.Turkish journal of emergency medicineArticle
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The early diagnosis and severity grading for acute pancreatitis (AP) are difficult to determine because of the complexity and differences in disease process. To date, few studies have investigated the role of lymphocyte ratio (LR) in AP. Therefore, the objective of the present study was to investigate the prognostic value of LR as an indicator in AP, as well as determine an optimal cut-off value for the severity prediction. There were two hundred four patients involved in this study, ninety-two of whom had severe acute pancreatitis (SAP). The LR was analyzed on admission and correlated with severity, which was determined using the Atlanta classification. The optimal cut-off value for LR was generated using receiving operator characteristic (ROC) curves. The results showed that the LR in the SAP group decreased significantly compared to the mild acute pancreatitis (MAP) group (8.82 vs. 13.43). The optimal cut-off value obtained from ROC curves was 0.081, with a sensitivity of 80.4%, a specificity of 53.3%, a positive likelihood ratio of 1.722, and a negative likelihood ratio of 0.368. In conclusion, the LR is obviously related to the condition of AP patients and is valuable for the differential diagnosis of SAP in early stages of AP.
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