Observational studyThe American journal of gastroenterology2017
Predictive Factors of Intestinal Necrosis in Acute Mesenteric Ischemia: Prospective Study from an Intestinal Stroke Center.
Observational study in The American journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 5 of them syntheses that pooled it.
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Who cites it
81 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Radiological diagnosis of acute mesenteric ischemia in adult patients: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Diagnostic accuracy of biomarkers to detect acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis.World journal of emergency surgery : WJES · 2023Pooled it
- Radiological predictive factors of transmural intestinal necrosis in acute mesenteric ischemia: systematic review and meta-analysis.European radiology · 2023Pooled it
- Incidence and outcomes of acute mesenteric ischaemia: a systematic review and meta-analysis.BMJ open · 2022Pooled it
- Predictors of bowel necrosis in patients with acute mesenteric ischemia: systematic review and meta-analysis.Updates in surgery · 2021Pooled it
- Venular-centered thrombo-inflammation drives microvascular failure after arterial recanalization in acute mesenteric ischemia.Communications medicine · 2026Article
- CT-based radiological score (AMESI CT-score) for severity of bowel injury in acute mesenteric ischemia.Abdominal radiology (New York) · 2026Article
- Current Evidence on the Use of Biomarkers for the Diagnosis of Acute Mesenteric Ischemia: A Narrative Review.Cureus · 2026Review
- DECT-based stratification of nonocclusive mesenteric ischemia using bowel-wall iodine concentration: a prospective single-center cohort.European radiology experimental · 2026Article
- Development and validation of machine learning-based prediction models for adult bowel necrosis for patients presenting with acute abdominal pain at the emergency department: a multicenter retrospective cohort study.BMC medical informatics and decision making · 2026Article
- Impact of surgical delay on bowel viability in internal hernia-related small bowel obstructon: a retrospective cohort study of clinical, imaging, and biochemical predictors of strangulation.BMC gastroenterology · 2026Article
- Malnutrition and Cachexia in Inpatients With Acute Cardiac Conditions: A Scientific Statement From the American Heart Association.Circulation · 2026Review
- Endovascular revascularization for treatment of acute mesenteric ischemia: a single-center experience.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026Article
- The Importance of Predicting Bowel Necrosis in Acute Mesenteric Ischemia: Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- The challenging diagnosis of ICU-related Mesenteric Ischaemia: a prospective, observational, multicentre cohort.Annals of intensive care · 2026Article
- Catastrophic STS/SVS type B3 aortic dissection complicated by hepatic portal venous gas and multi-organ malperfusion: a case report.Frontiers in medicine · 2026Article
- Combined endovascular and surgical management of acute superior mesenteric artery embolism complicated by intestinal necrosis: a case report.Frontiers in medicine · 2026Article
- Computed tomography findings and surgical outcomes in acute mesenteric ischemia: a retrospective single-center cohort study.Frontiers in surgery · 2026Article
- Non-enhancing bowel dilatation and secondary ileus on CT as a surgical red flag in geriatric patients with atypical presentations.BMC geriatrics · 2025Article
- Diagnostic value of dual-energy computed tomography in irreversible transmural intestinal necrosis in patients with acute occlusive mesenteric ischemia.World journal of gastrointestinal surgery · 2025Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo identify predictive factors for irreversible transmural intestinal necrosis (ITIN) in acute mesenteric ischemia (AMI) and establish a risk score for ITIN.
methodsThis single-center prospective cohort study was performed between 2009 and 2015 in patients with AMI. The primary outcome was the occurrence of ITIN, confirmed by specimen analysis in patients who underwent surgery. Patients who recovered from AMI with no need for intestinal resection were considered not to have ITIN. Clinical, biological and radiological data were compared in a Cox regression model.
resultsA total of 67 patients were included. The origin of AMI was arterial, venous, or non-occlusive in 61%, 37%, 2% of cases, respectively. Intestinal resection and ITIN concerned 42% and 34% of patients, respectively. Factors associated with ITIN in multivariate analysis were: organ failure (hazard ratio (HR): 3.1 (95% confidence interval (CI): 1.1-8.5); P=0.03), serum lactate levels >2 mmol/l (HR: 4.1 (95% CI: 1.4-11.5); P=0.01), and bowel loop dilation on computerized tomography scan (HR: 2.6 (95% CI: 1.2-5.7); P=0.02). ITIN rate increased from 3% to 38%, 89%, and 100% in patients with 0, 1, 2, and 3 factors, respectively. Area under the receiver operating characteristics curve for the diagnosis of ITIN was 0.936 (95% CI: 0.866-0.997) depending on the number of predictive factors.
conclusionsWe identified three predictive factors for irreversible intestinal ischemic injury requiring resection in the setting of AMI. Close monitoring of these factors could help avoid unnecessary laparotomy, prevent resection, as well as complications due to unresected necrosis, and possibly lower the overall mortality.
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