Trial reportDeutsches Arzteblatt international2017
Should Screening Colonoscopy Be Offered From Age 50?
Trial report in Deutsches Arzteblatt international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Early-Age Onset Colorectal Neoplasia in Average-Risk Individuals Undergoing Screening Colonoscopy: A Systematic Review and Meta-Analysis.Gastroenterology · 2021Pooled it
- The Effects of Differing Invitation Models on the Uptake of Immunological Fecal Occult Blood Testing.Deutsches Arzteblatt international · 2020Trial
- Invitation to Screening Colonoscopy in the Population at Familial Risk for Colorectal Cancer.Deutsches Arzteblatt international · 2018Trial
- Colonoscopy Versus Fecal Occult Blood Test Versus No Screening: A Comparative Analysis of Long-Term Effects.Deutsches Arzteblatt international · 2026Observational
- Age-specific sequence of colorectal cancer screening options in Germany: A model-based critical evaluation.PLoS medicine · 2020Article
- Helicobacter pylori infection associated with an increased risk of colorectal adenomatous polyps in the Chinese population.BMC gastroenterology · 2019Article
- Avoidable Cancer Mortality in Germany Since Reunification: Regional Variation and Sex Differences.Frontiers in public health · 2019Article
- A review of sex-related differences in colorectal cancer incidence, screening uptake, routes to diagnosis, cancer stage and survival in the UK.BMC cancer · 2018Article
- Individual invitation letters lead to significant increase in attendance for screening colonoscopies: Results of a pilot study in Northern Hesse, Germany.United European gastroenterology journal · 2018Article
- Colonoscopy in Germany-Important Steps Towards a National Screening Program.Deutsches Arzteblatt international · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe introduction of colonoscopic screening in 2002 for persons aged 55 and older was followed by a marked decline in the incidence of colon cancer in the corresponding age groups in Germany. The prevalence of colorectal neoplasia among persons aged 50 to 54 has remained unknown until now. Expert committees currently recommend colonoscopic screening for persons aged 50 and older. This option has been offered since 2014 by the AOK Baden-Württemberg and by Bosch BKK in the framework of their specialized medical care program.
methodsIn April 2014 and 2015, 84 726 insurees aged 50-54 were invited by mail to participate in colonoscopic screening. The utilization and results of colonoscopic screening were studied. A questionnaire about risks was additionally sent to half of the participants, who were selected at random (study registration: DRKS00006268).
resultsWithin one year, 1.9% of persons to whom invitations had been sent took up the offer of colonoscopic screening; these persons included 3.3% of those already enrolled in the specialized medical care program. The 1396 colonoscopies that were performed revealed advanced neoplasia (colon cancer or advanced adenoma) in 6.8% of cases. The prevalence of advanced neoplasia among men aged 50 to 54 was nearly twice as high as that among women in the same age group (8.6% vs. 4.5%, p = 0.0027). It was also higher than the prevalences documented in the German nationwide cancer registry for women aged 55 to 79. The additional sending of a risk questionnaire along with the invitation had no effect on the rate of detection of relevant findings or on the rate of participation in colonoscopic screening.
conclusionThese findings lend support to the demand that the offer of colonoscopic screening should be extended at least to men aged 50 and above.
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