ArticleMolecular neurobiology2018
Differences in 5-HT2A and mGlu2 Receptor Expression Levels and Repressive Epigenetic Modifications at the 5-HT2A Promoter Region in the Roman Low- (RLA-I) and High- (RHA-I) Avoidance Rat Strains.
Abstract readComparative Study
In one paragraph
Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19citing papers in PubMed
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Who cites it
19 citing papers in PubMed.
- 5-HTPharmacological reviews · 2025Review
- Aberrant glutamatergic systems underlying impulsive behaviors: Insights from clinical and preclinical research.Progress in neuro-psychopharmacology & biological psychiatry · 2024Review
- Contrasting Effects of Oxytocin on MK801-Induced Social and Non-Social Behavior Impairment and Hyperactivity in a Genetic Rat Model of Schizophrenia-Linked Features.Brain sciences · 2024Article
- Epigenetic Modulation of GPER Expression in Gastric and Colonic Smooth Muscle of Male and Female Non-Obese Diabetic (NOD) Mice: Insights into H3K4me3 and H3K27ac Modifications.International journal of molecular sciences · 2024Article
- Sex-specific epigenetics drive low GPER expression in gastrointestinal smooth muscles in type 2 diabetic mice.Scientific reports · 2024Article
- Schizophrenia in the genetic era: a review from development history, clinical features and genomic research approaches to insights of susceptibility genes.Metabolic brain disease · 2024Review
- Reduced Expression of the Htr2a, Grin1, and Bdnf Genes and Cognitive Inflexibility in a Model of High Compulsive Rats.Molecular neurobiology · 2023Article
- Atypical antipsychotics attenuate MK801-induced social withdrawal and hyperlocomotion in the RHA rat model of schizophrenia-relevant features.Psychopharmacology · 2023Article
- Contribution of the Roman rat lines/strains to personality neuroscience: neurobehavioral modeling of internalizing/externalizing psychopathologies.Personality neuroscience · 2023Review
- Pharmacological and Physiological Correlates of the Bidirectional Fear Phenotype of the Carioca Rats and Other Bidirectionally Selected Lines.Current neuropharmacology · 2023Review
- Neurobehavioral Profiles of Six Genetically-based Rat Models of Schizophrenia- related Symptoms.Current neuropharmacology · 2023Article
- Neurobehavioral and neurodevelopmental profiles of a heuristic genetic model of differential schizophrenia- and addiction-relevant features: The RHA vs. RLA rats.Neuroscience and biobehavioral reviews · 2021Review
- Dopamine D2/3 Receptor Availabilities and Evoked Dopamine Release in Striatum Differentially Predict Impulsivity and Novelty Preference in Roman High- and Low-Avoidance Rats.The international journal of neuropsychopharmacology · 2021Article
- Increased thin-spine density in frontal cortex pyramidal neurons in a genetic rat model of schizophrenia-relevant features.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2021Article
- Metabotropic Glutamate Receptor 2 and Dopamine Receptor 2 Gene Expression Predict Sensorimotor Gating Response in the Genetically Heterogeneous NIH-HS Rat Strain.Molecular neurobiology · 2020Article
- Long-term probiotic intervention mitigates memory dysfunction through a novel H3K27me3-based mechanism in lead-exposed rats.Translational psychiatry · 2020Article
- Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Article
- A Genetic Model of Impulsivity, Vulnerability to Drug Abuse and Schizophrenia-Relevant Symptoms With Translational Potential: The Roman High- vs. Low-Avoidance Rats.Frontiers in behavioral neuroscience · 2019Article
- Coping-Style Behavior Identified by a Survey of Parent-of-Origin Effects in the Rat.G3 (Bethesda, Md.) · 2018Article
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Authors and funding
15 authors.
Luna FomsgaardResearch Laboratory for Stereology and Neuroscience, Bispebjerg and Frederiksberg Hospitals, Building 11B, 2nd floor, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark.
Jose L MorenoDepartment of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA.
Mario de la Fuente RevengaDepartment of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA.
Tomasz BrudekResearch Laboratory for Stereology and Neuroscience, Bispebjerg and Frederiksberg Hospitals, Building 11B, 2nd floor, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark.
Dea AdamsenResearch Laboratory for Stereology and Neuroscience, Bispebjerg and Frederiksberg Hospitals, Building 11B, 2nd floor, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark.
Cristobal Rio-AlamosDepartamento de Psiquiatria y Medicina Legal, Instituto de Neurociencias, Universidad Autonoma de Barcelona, Barcelona, Spain.
Justin SaundersDepartment of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA.
Anders Bue KleinDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Ignasi OliverasDepartamento de Psiquiatria y Medicina Legal, Instituto de Neurociencias, Universidad Autonoma de Barcelona, Barcelona, Spain.
Toni CañeteDepartamento de Psiquiatria y Medicina Legal, Instituto de Neurociencias, Universidad Autonoma de Barcelona, Barcelona, Spain.
Gloria BlazquezDepartamento de Psiquiatria y Medicina Legal, Instituto de Neurociencias, Universidad Autonoma de Barcelona, Barcelona, Spain.
Adolf TobeñaDepartamento de Psiquiatria y Medicina Legal, Instituto de Neurociencias, Universidad Autonoma de Barcelona, Barcelona, Spain.
Albert Fernandez-TeruelDepartamento de Psiquiatria y Medicina Legal, Instituto de Neurociencias, Universidad Autonoma de Barcelona, Barcelona, Spain.
Javier Gonzalez-MaesoDepartment of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA.
Susana AznarResearch Laboratory for Stereology and Neuroscience, Bispebjerg and Frederiksberg Hospitals, Building 11B, 2nd floor, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark. Susana.aznar.kleijn@regionh.dk.ORCID http://orcid.org/0000-0001-7940-6246
Funding
Structure and function of the 5HT2A/mGluR2 complex in schizophreniaR01MH084894 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI Javier Gonzalez-Maeso · 2009 to 2026
$6.8MPreclinical role of HDAC2 in mGlu2-dependent schizophrenia treatmentR01MH111940 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI GONZÁLEZ-MAESO, JAVIER · 2017 to 2021
$1.5MFI-DGR 2014SGR-1587Ministerio de Economía, Industria y Competitividad (ES) PSI2013-41872-PNIH HHS R01MH084894NIMH NIH HHS R01 MH084894NIMH NIH HHS R01 MH111940
Abstract
The serotonin 2A (5-HT
Indexed as
AnimalsAvoidance LearningEpigenesis, GeneticGene ExpressionMalePromoter Regions, GeneticRatsRats, TransgenicReceptor, Serotonin, 5-HT2AReceptors, Metabotropic GlutamateSpecies Specificitymetabotropic glutamate receptor 2Receptor, Serotonin, 5-HT2AReceptors, Metabotropic Glutamate5-HT2AEpigeneticsGSK3βmGluR2Prefrontal cortexRoman low- and high-avoidance ratsSchizophreniaStriatumβ-Catenin
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