Evidence map›Paper›PMID 28265827›Full record

SynthesisDigestive diseases and sciences2017

Association of Helicobacter pylori with Chronic Kidney Diseases: A Meta-Analysis.

Karn Wijarnpreecha, Charat Thongprayoon, Pitchaphon Nissaisorakarn, Veeravich Jaruvongvanich, Kiran Nakkala, Ridhmi Rajapakse, Wisit Cheungpasitporn

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Gut and liver · 2019
    Pooled it
  2. Pooled it
  3. Pooled it
  4. The Detection ofPathogens (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Assessing the Relationship betweenHealthcare (Basel, Switzerland) · 2021
    Article
  8. Article
  9. Review
  10. Prevalence ofGut and liver · 2019
    Article
  11. Association betweenRenal failure · 2019
    Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Karn WijarnpreechaDepartment of Internal Medicine, Bassett Medical Center, One Atwell Road, Cooperstown, NY, 13326, USA. dr.karn.wi@gmail.com.
Charat ThongprayoonDepartment of Internal Medicine, Bassett Medical Center, One Atwell Road, Cooperstown, NY, 13326, USA.
Pitchaphon NissaisorakarnDepartment of Internal Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Veeravich JaruvongvanichDepartment of Internal Medicine, University of Hawaii, Honolulu, HI, USA.
Kiran NakkalaCape Fear Center for Digestive Disease, P.A., Fayetteville, NC, USA.
Ridhmi RajapakseDepartment of Internal Medicine, Bassett Medical Center, One Atwell Road, Cooperstown, NY, 13326, USA.
Wisit CheungpasitpornDivision of Nephrology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Bassett Medical Center · USCape Fear Valley Medical Center · USJacobi Medical Center · USMayo Clinic in Arizona · USUniversity of Hawaii System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe reported risk of chronic kidney disease (CKD) in patients with Helicobacter pylori infection is conflicting. This meta-analysis was conducted to summarize all available data and to estimate the prevalence and association between H. pylori and kidney disease and CKD.

methodsComprehensive literature review was conducted using MEDLINE and EMBASE database through October 2016 to identify studies that reported the prevalence or the association between H. pylori infection and non-dialysis-dependent kidney diseases or CKD. Effect estimates from the individual study were extracted and combined using random-effect, generic inverse variance method of DerSimonian and Laird.

resultsOf 4546 studies, nine cross-sectional studies met the eligibility criteria and were included in the meta-analysis. The estimated prevalence of H. pylori infection among subjects with kidney disease was 53% (95% CI 45-61%). The pooled OR of H. pylori in patients with non-dialysis-dependent kidney diseases was 1.20 (95% CI 0.73-1.97) when compared with the patients without kidney diseases. The meta-analysis was then limited to only studies evaluating the risk of H. pylori in CKD; the pooled OR of H. pylori in patients with CKD was 1.00 (95% CI 0.58-1.71).

conclusionsThe estimated prevalence of H. pylori in patients with non-dialysis-dependent kidney diseases is 53%. This study does not support the association between H. pylori infection and non-dialysis-dependent kidney diseases nor CKD.

Indexed as

Helicobacter pyloriCross-Sectional StudiesHelicobacter InfectionsHumansPrevalenceRenal Insufficiency, ChronicCampylobacterChronic kidney diseaseHelicobacter pyloriMeta-analysisRenal disease

Identifiers

PMID28265827
OpenAlexW2591804752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.