ArticleBreast cancer research and treatment2017
Lymphatico-venous anastomosis as treatment for breast cancer-related lymphedema: a prospective study on quality of life.
Article in Breast cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Animal Models of Lymphaticovenous Anastomosis: A Systematic Review of Current Evidence and Future Directions in Translational Research.Microsurgery · 2026Pooled it
- Lymphovenous bypass for the treatment of secondary lymphedema: A meta-analysis of prospective outcomes.Breast cancer research and treatment · 2025Pooled it
- Pooled it
- Efficacy and safety assessment of lymphovenous anastomosis in patients with primary and secondary lymphoedema: A systematic review of prospective evidence.Microsurgery · 2019Pooled it
- Economic evaluation of lymphaticovenous anastomosis versus conservative therapy for breast cancer-related lymphoedema: secondary outcome analysis of a randomized clinical trial.The British journal of surgery · 2026Trial
- The 6 month interim analysis of a randomized controlled trial assessing the quality of life in patients with breast cancer related lymphedema undergoing lymphaticovenous anastomosis vs. conservative therapy.Scientific reports · 2024Trial
- Review
- Macrophages recruited by implanted fibrin gels promote regeneration of injured lymphatic vessels.Scientific reports · 2026Article
- A Prospective Study of the Impact of Lymphatic Venous Anastomosis as a Treatment for Lymphedema.Plastic and reconstructive surgery. Global open · 2025Article
- Surgical Treatment, Rehabilitative Approaches and Functioning Assessment for Patients Affected by Breast Cancer-Related Lymphedema: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2025Review
- Article
- Surgical treatment algorithm for breast cancer lymphedema-a systematic review.Gland surgery · 2024Review
- Surgical management of breast cancer-related lymphedema: a narrative review of contemporary practices.Annals of translational medicine · 2023Review
- The Quality of Life after Lymphaticovenous Anastomosis in 118 Lower Limb Lymphedema Patients.Archives of plastic surgery · 2023Article
- Development and Psychometric Validation of a Patient-Reported Outcome Measure for Arm Lymphedema: The LYMPH-Q Upper Extremity Module.Annals of surgical oncology · 2021Article
- Outcomes of Lymphovenous Anastomosis for Upper Extremity Lymphedema: A Systematic Review.Plastic and reconstructive surgery. Global open · 2021Review
- Outcomes following lymphaticovenous anastomosis (LVA) for 100 cases of lymphedema: results over 24-months follow-up.Breast cancer research and treatment · 2020Article
- Surgical Approach to Lymphedema Reduction.Current oncology reports · 2020Review
- Lymphaticovenular anastomosis for breast cancer-related upper extremity lymphedema: a literature review.Gland surgery · 2020Review
- Systematic Review of Patient-Reported Outcomes following Surgical Treatment of Lymphedema.Cancers · 2020Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLymphedema is a chronic and disabling sequel of breast cancer treatment that can be treated by lymphatico-venous anastomosis (LVA). Artificial connections between the venous and lymphatic system are performed supermicrosurgically. This prospective study analyses the effect of LVA on quality of life.
methodsA prospective study was performed between November 2015 and July 2016 on consecutive patients in the Maastricht University Medical Centre. Quality of life was considered as the primary outcome, and the Lymphedema International Classification of Functioning (Lymph-ICF) questionnaire was used. Discontinuation of compressive stockings and arm volume, using the Upper Extremity Lymphedema index (UEL-index), were the secondary outcomes.
resultsTwenty women with early-stage breast cancer-related lymphedema (BCRL) were included. The mean age was 55.9 ± 4 years and the median BMI was 25.1 [21-30] kg/m
conclusionsLVA for early-stage BCRL resulted in a significant improvement in quality of life and a high rate in stocking discontinuation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.