ReviewEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2017
Silver-coated megaprostheses: review of the literature.
Review in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gentamicin-Coated Tibia Nail in Fractures and Nonunion to Reduce Fracture-Related Infections: A Systematic Review.Molecules (Basel, Switzerland) · 2020Pooled it
- The Standardization and Comparability Gap in Evaluating Antibacterial Surfaces for Load-Bearing Orthopedic Implants: A Critical Review.Bioengineering (Basel, Switzerland) · 2026Review
- Treatment of Periprosthetic Joint Infection After Tumor Megaprosthetic Reconstruction: A Narrative Review.Cancers · 2026Review
- CORR Insights®: Can Periprosthetic Joint Infection of Tumor Prostheses Be Controlled With Debridement, Antibiotics, and Implant Retention?Clinical orthopaedics and related research · 2025Article
- Potential role of metal nanoparticles in treatment of peri-implant mucositis and peri-implantitis.Biomedical engineering online · 2024Review
- Characteristics and Epidemiology of Megaprostheses Infections: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Biocompatibility and Antibacterial Properties of NiTiAg Porous Alloys for Bone Implants.ACS omega · 2024Article
- Topical Application of Vancomycin Powder to Prevent Infections after Massive Bone Resection and the implantation of Megaprostheses in Orthopaedic Oncology Surgery.Malaysian orthopaedic journal · 2024Article
- Shock Wave-Activated Silver-Loaded Biopolymer Implant Coating EliminatesPharmaceutics · 2023Article
- On-Demand Release of Anti-Infective Silver from a Novel Implant Coating Using High-Energy Focused Shock Waves.Pharmaceutics · 2023Article
- Surgical Site Infection after Bone Tumor Surgery: Risk Factors and New Preventive Techniques.Cancers · 2022Review
- Mid-term implant survival, functional and radiological results and mechanical complications of mega-prosthetic reconstruction around the knee with the PENTA® system.Archives of orthopaedic and trauma surgery · 2022Article
- Long-term changes in serum silver concentrations after extremity reconstruction with silver-coated megaprostheses.Scientific reports · 2022Article
- The Performances of Conventional Titanium and Silver-Coated Megaprostheses in Non-oncological and Post-oncological Patients: An Analysis of Infection Failures in 142 Patients.The archives of bone and joint surgery · 2022Article
- Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection.Cancers · 2022Review
- [Tumour arthroplasty].Der Orthopade · 2021Article
- Recent Strategies to Combat Infections from Biofilm-Forming Bacteria on Orthopaedic Implants.International journal of molecular sciences · 2021Review
- Megaprosthesis Versus Allograft Prosthesis Composite for the Management of Massive Skeletal Defects: A Meta-Analysis of Comparative Studies.Current reviews in musculoskeletal medicine · 2021Review
- Time-dependent efficacy of combination of silver-containing hydroxyapatite coating and vancomycin on methicillin-resistant Staphylococcus aureus biofilm formation in vitro.BMC research notes · 2021Article
- Fighting Megaprosthetic Infections: What are the Chances of Winning?Indian journal of orthopaedics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periprosthetic infection remains one of the most serious complications following megaendoprostheses. Despite a large number of preventive measures that have been introduced in recent years, it has not been possible to further reduce the rate of periprosthetic infection. With regard to metallic modification of implants, silver in particular has been regarded as highly promising, since silver particles combine a high degree of antimicrobial activity with a low level of human toxicity. This review provides an overview of the history of the use of silver as an antimicrobial agent, its mechanism of action, and its clinical application in the field of megaendoprosthetics. The benefits of silver-coated prostheses could not be confirmed until now. However, a large number of retrospective studies suggest that the rate of periprosthetic infections could be reduced by using silver-coated megaprostheses.
Indexed as
Identifiers
28265758What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.