Evidence map›Paper›PMID 28265546›Full record

ArticleAvicenna journal of phytomedicine

Protective effect of pomegranate seed oil against H

Mehdi Bihamta, Azar Hosseini, Ahmad Ghorbani, Mohammad Taher Boroushaki

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03732586 (Effect of Omega-5 Fatty Acid Supplement on Markers of Inflammation and Oxidative Stress in Patients With Severe Alcoholic Hepatitis Treated With Prednisone), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03732586 nacompletednot on this map

Effect of Omega-5 Fatty Acid Supplement on Markers of Inflammation and Oxidative Stress in Patients With Severe Alcoholic Hepatitis Treated With Prednisone

TypeinterventionalSponsorHospital General Dr. Manuel Gea GonzálezRan2018 to 2023Enrolled40ConditionsAlcoholic HepatitisArmsOmega 5 fatty acid supplement, PLACEBO
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. The Effect of Hydro-alcoholic Extract ofInternational journal of preventive medicine · 2020
    Article
  9. [Activation of aldehyde dehydrogenase 2 alleviates HNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018
    Article
  10. Article
  11. Orexin-A protects SH-SY5Y cells against HInternational journal of immunopathology and pharmacology
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mehdi BihamtaDepartment of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Azar HosseiniPharmacological Research Center of Medicinal Plants, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ahmad GhorbaniPharmacological Research Center of Medicinal Plants, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Taher BoroushakiDepartment of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Pharmacological Research Center of Medicinal Plants, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIt has been well documented that oxidative stress is involved in the pathogenesis of cardiac diseases. Previous studies have shown that pomegranate seed oil (PSO) has antioxidant properties. This study was designed to investigate probable protective effects of PSO against hydrogen peroxide (H MATERIALS AND

methodsThe cells were pretreated 24 hr with PSO 1 hr before exposure to 200 µM H

resultsH

conclusionPSO has protective effect against oxidative stress-induced damage in cardiomyocytes and can be considered as a natural cardioprotective agent to prevent cardiovascular diseases.

Indexed as

CardiomyocytesOxidative stressPomegranate seedReactive oxygen speciesSuper oxide dismutase

Identifiers

PMID28265546
PMCPMC5329176
OpenAlexW2400395252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.