Evidence map›Paper›PMID 28265360›Full record

ArticleFood science & nutrition2017

A nutritional supplement containing lactoferrin stimulates the immune system, extends lifespan, and reduces amyloid

Patricia Martorell, Silvia Llopis, Nuria Gonzalez, Daniel Ramón, Gabriel Serrano, Ana Torrens, Juan M Serrano, Maria Navarro, Salvador Genovés

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05783180 (A Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study to Evaluate the Safety and Efficacy of Sesderma LACTYFERRIN™ Forte and Sesderma ZINC Defense™), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05783180 phase2withdrawnnot on this mapstarted 2023, after this paper: background citation

A Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study to Evaluate the Safety and Efficacy of Sesderma LACTYFERRIN™ Forte and Sesderma ZINC Defense™ (Liposomal Bovine Lactoferrin (LbLf) and Liposomal Zn (LZn)) and Standard of Care (SOC) vs SOC in the Treatment of Non-hospitalized Patients With COVID-19

TypeinterventionalSponsorJose David Suarez, MDRan2023 to 2024Enrolled0ConditionsCOVID-19ArmsSesderma LACTYFERRIN™ Forte and Sesderma ZINC Defense™, Placebo
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. An Update of Salivary Biomarkers for the Diagnosis of Alzheimer's Disease.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Effects of Lactoferrin andAnimals : an open access journal from MDPI · 2024
    Article
  7. Neuroprotective effects of a novel peptide fromFood science & nutrition · 2023
    Article
  8. Article
  9. Toxics · 2023
    Review
  10. The role of microbiome-host interactions in the development of Alzheimer´s disease.Frontiers in cellular and infection microbiology · 2023
    Review
  11. Article
  12. The Lactoferrin Phenomenon-A Miracle Molecule.Molecules (Basel, Switzerland) · 2022
    Review
  13. Current research in food science · 2022
    Review
  14. Article
  15. Review
  16. Article
  17. ProbioticFrontiers in cellular and infection microbiology · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Patricia MartorellCell Biology Laboratory Food Biotechnology Department Biópolis SL Paterna, Valencia 46980 Spain.
Silvia LlopisCell Biology Laboratory Food Biotechnology Department Biópolis SL Paterna, Valencia 46980 Spain.
Nuria GonzalezCell Biology Laboratory Food Biotechnology Department Biópolis SL Paterna, Valencia 46980 Spain.
Daniel RamónCell Biology Laboratory Food Biotechnology Department Biópolis SL Paterna, Valencia 46980 Spain.
Gabriel SerranoResearch and Development Department Sesderma Laboratories Rafelbuñol, Valencia 46138 Spain.
Ana TorrensResearch and Development Department Sesderma Laboratories Rafelbuñol, Valencia 46138 Spain.
Juan M SerranoResearch and Development Department Sesderma Laboratories Rafelbuñol, Valencia 46138 Spain.
Maria NavarroResearch and Development Department Sesderma Laboratories Rafelbuñol, Valencia 46138 Spain.
Salvador GenovésCell Biology Laboratory Food Biotechnology Department Biópolis SL Paterna, Valencia 46980 Spain.
Biopolis (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactoferrin is a highly multifunctional glycoprotein involved in many physiological functions, including regulation of iron absorption and immune responses. Moreover, there is increasing evidence for neuroprotective effects of lactoferrin. We used

Indexed as

Alzheimer's diseaseCaenorhabditis elegansimmune systemlactoferrinneuroprotection

Identifiers

PMID28265360
PMCPMC5332254
OpenAlexW2485093029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.