Evidence map›Paper›PMID 28265325›Full record

ReviewCanadian Urological Association journal = Journal de l'Association des urologues du Canada

Overactive bladder in children.

Sophie Ramsay, Stéphane Bolduc

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Canadian Urological Association journal = Journal de l'Association des urologues du Canada. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07046156 (Evaluation of Anticholinergic Treatment Response and Predictive Factors in Pediatric Overactive Bladder), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07046156 active not recruitingnot on this map

Evaluation of Anticholinergic Treatment Response and Predictive Factors in Pediatric Overactive Bladder

TypeobservationalSponsorSehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research HospitalRan2022 to 2026Enrolled120ConditionsOveractive BladderArmsOxybutynin Cl, propiverine, Tolterodine
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  7. Observational
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  12. Updates of Overactive Bladder in Pediatrics.International neurourology journal · 2023
    Article
  13. First North American experience of propiverine use in children with overactive bladder.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sophie RamsayDivision of Urology, CHU de Québec-Université Laval, Quebec City, QC Canada.
Stéphane BolducDivision of Urology, CHU de Québec-Université Laval, Quebec City, QC Canada;; CRCHU de Québec-Université Laval, Quebec City, QC, Canada and Axe Médecine Régénératrice.
Université Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overactive bladder (OAB) is a highly prevalent disorder in the pediatric population. This condition is especially troublesome for pediatric patients and their families when associated with incontinence, since it negatively affects self-esteem and impairs children's development. From the patient's perspective, urgency and urge incontinence can have a significant impact, negatively affecting their quality of life. For a therapy to have true benefit, changes must not only be statistically significant, but must also be perceived as meaningful by the patient. A stepwise approach is favoured to treat this pathology, starting with behavioural therapy, followed by medical management, and eventually more invasive procedures. Antimuscarinic agents are the mainstay of medical treatment for OAB. Oxybutynin is the most commonly used antimuscarinic in the pediatric population. However, some patients have a suboptimal response to antimuscarinics and many experience bothersome side effects, which have been documented with all antimuscarinics to a significantly higher degree than placebo. Although there have been reports about the use of tolterodine, fesoterodine, trospium, propiverine, and solifenacin in children, to date, only oxybutynin has been officially approved for pediatric use by medical authorities in North America. This review will address alternative treatment options for pediatric patients presenting with OAB, from conservative measures to more invasive therapies.

Identifiers

PMID28265325
PMCPMC5332242
OpenAlexW2587921420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.