Evidence map›Paper›PMID 28265259›Full record

ArticleFrontiers in neurology2017

Remodeling Brain Activity by Repetitive Cervicothoracic Transspinal Stimulation after Human Spinal Cord Injury.

Lynda M Murray, Maria Knikou

3 registry-linked trialsOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03669302 naterminatednot on this mapstarted 2018, after this paper: background citation

Activity-Dependent Transspinal Stimulation for Recovery of Walking Ability After Spinal Cord Injury

TypeinterventionalSponsorCity University of New YorkRan2018 to 2021Enrolled10ConditionsSpinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, SpasticArmsRobotic gait training, Robotic gait training and low-frequency transspinal stimulation, Robotic gait training and high-frequency transspinal stimulation
NCT04807764 nacompletednot on this mapstarted 2021, after this paper: background citation

Priming With High-Frequency Trans-spinal Stimulation to Augment Locomotor Benefits in Spinal Cord Injury

TypeinterventionalSponsorCity University of New YorkRan2021 to 2024Enrolled14ConditionsSpinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, SpasticArmsStanding transspinal stimulation followed by robotic gait training, Lying transspinal stimulation followed by robotic gait training, Standing sham transspinal stimulation followed by robotic gait training
NCT07204184 narecruitingnot on this mapstarted 2026, after this paper: background citation

Cervical and Lumbosacral Transspinal Stimulation to Reconnect the Injured Human Spinal Cord

TypeinterventionalSponsorMaria Knikou, PT, MBA, PhDRan2026 to 2028Enrolled36ConditionsSpinal Cord Injuries (Complete and Incomplete)ArmsMultisite transspinal stimulation at rest, Multisite transspinal stimulation during robotic gait training
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  7. Timing-dependent synergies between noninvasive motor cortex and spinal cord stimulation in chronic cervical spinal cord injury.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lynda M MurrayMotor Control and NeuroRecovery Laboratory, Department of Physical Therapy, College of Staten Island, New York, NY, USA; Departments of Neuroscience and Biology, Graduate Center, City University of New York, New York, NY, USA.
Maria KnikouMotor Control and NeuroRecovery Laboratory, Department of Physical Therapy, College of Staten Island, New York, NY, USA; Departments of Neuroscience and Biology, Graduate Center, City University of New York, New York, NY, USA.
College of Staten Island · USThe Graduate Center, CUNY · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interventions that can produce targeted brain plasticity after human spinal cord injury (SCI) are needed for restoration of impaired movement in these patients. In this study, we tested the effects of repetitive cervicothoracic transspinal stimulation in one person with cervical motor incomplete SCI on cortical and corticospinal excitability, which were assessed

Indexed as

cortical plasticitycorticospinal plasticityprimary motor cortexrepetitive transspinal stimulationspinal cord injury

Identifiers

PMID28265259
PMCPMC5316528
OpenAlexW2587949408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.