ArticleRadiology and oncology2017
Primary pulmonary choriocarcinoma.
Article in Radiology and oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 34 citations in OpenAlex.
- A Rare Case of Multimetastatic Choriocarcinoma.Diagnostics (Basel, Switzerland) · 2026Article
- A Rare Case of Primary Pulmonary Choriocarcinoma Metastasizing to the Kidney: Diagnostic and Therapeutic Complexities.Cancer reports (Hoboken, N.J.) · 2026Article
- Clinicopathological and molecular characteristics of primary pulmonary choriocarcinoma: a case report and systematic review.Frontiers in oncology · 2026Article
- Clinicopathological features of primary pulmonary choriocarcinoma in males: A report of two cases and literature review.Respiratory medicine case reports · 2026Article
- The role of cranial radiotherapy in managing neurological symptoms of brain metastases from pulmonary choriocarcinoma: a case report and literature review.Discover oncology · 2025Article
- A Histological Conundrum With a Distinctive Biochemical Marker: A Case Report of Primary Pulmonary Choriocarcinoma.Cureus · 2025Article
- Primary Pulmonary Choriocarcinoma With Lymph Node Metastasis: A Case Report and Brief Review.Cureus · 2024Article
- Article
- A drastic post operative course after the resection of primary pulmonary choriocarcinoma in a male.Respirology case reports · 2024Article
- A Case Report on Primary Pulmonary Choriocarcinoma.Cureus · 2024Article
- Case report: Molecular profiling facilitates the diagnosis of a challenging case of lung cancer with choriocarcinoma features.Frontiers in oncology · 2024Article
- A poor prognostic male choriocarcinoma with multiple systemic metastases: a case report and the literature review.Frontiers in medicine · 2024Article
- Beta-HCG Secretion by a Pulmonary Choriocarcinoma in a Male Patient.Case reports in oncological medicine · 2024Article
- A remarkable response to combination chemotherapy with nivolumab and ipilimumab in a patient with primary pulmonary choriocarcinoma: a case report.Translational cancer research · 2023Article
- Analysis of clinical characteristics and prognosis of 68 patients with primary pulmonary choriocarcinoma.BMC pulmonary medicine · 2023Article
- Case Report: Treatment of primary pulmonary choriocarcinoma with lung lobectomy and adjuvant chemotherapy.Gynecologic oncology reports · 2022Article
- Primary Pulmonary Choriocarcinoma Treated With Neoadjuvant Chemotherapy and Lobectomy: A Case Report.Cureus · 2022Article
- Case report: Using DNA short tandem repeats to confirm nongestational origin of pulmonary choriocarcinoma.Frontiers in oncology · 2022Article
- Amenorrhea and elevated βhuman chorionic gonadotropin of unknown origin: An unexpected location of choriocarcinoma.Gynecologic oncology reports · 2021Article
- Choriocarcinoma Presenting as a Pleural Effusion.Cureus · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the study was to establish whether there are different clinical entities of primary pulmonary choriocarcinoma (PPC) that deserve different diagnostic approach and the most optimal treatment. PATIENTS AND
methodsA systematic review with PubMed search was conducted to identify studies that reported cases of PPC. The eligibility criteria were histological diagnosis of pulmonary choriocarcinoma and thorough examination of the reproductive organs to exclude potential primary choriocarcinoma in the gonads. Furthermore, to illustrate the review we additionally present a patient referred at our institution.
results55 cases (17 men) were included in the review with a median age of 34 years. Women with the history of gestational event showed better survival outcome than women without the history of gestational event. Patients treated with combined modality treatment (surgery and chemotherapy) survived longer than the patients without combined modality treatment. Furthermore, multivariate analysis of prognostic factors showed that the combined modality treatment had independent prognostic significance. Size of the tumour showed significant prognostic influence in univariate and multivariate analysis.
conclusionsPPC is an extreme rarity with variable clinical characteristics and outcome. It is important to capture and treat patients in the early stages of the disease. Women with the history of gestational event may show better survival, therefore genetic examination could help us to predict patient's prognosis. Surgery followed by adjuvant chemotherapy appears to represent the best treatment for PPC.
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