Evidence map›Paper›PMID 28265051›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus

Tiago Leao, Guilherme Castelão, Anton Korobeynikov, Emily A Monroe, Sheila Podell, Evgenia Glukhov, Eric E Allen, William H Gerwick, Lena Gerwick

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Peptide Prenylation Follows Divergent Substrate Engagement Rules.Journal of the American Chemical Society · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Fatuamide A, a Hybrid PKS/NRPS Metallophore from aJournal of natural products · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Heterologous production of cyanobacterial compounds.Journal of industrial microbiology & biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tiago LeaoCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
Guilherme CastelãoClimate, Atmospheric Sciences, and Physical Oceanography, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
Anton KorobeynikovDepartment of Statistical Modelling, St. Petersburg State University, Saint Petersburg 198504, Russia.ORCID 0000-0002-2937-9259
Emily A MonroeDepartment of Biology, William Paterson University, Wayne, NJ 07470.
Sheila PodellCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
Evgenia GlukhovCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
Eric E AllenCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
William H GerwickCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
Lena GerwickCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093; lgerwick@ucsd.edu.

Funding

Unified Computation Tools for Natural Products ResearchR01GM107550 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COTTRELL, GARRISON W, GERWICK, WILLIAM HENRY · 2013 to 2025
$8.2M
Biosynthetic Analysis of Marine Cyanobacterial PathwaysR01CA108874 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GERWICK, WILLIAM HENRY, SHERMAN, DAVID H · 2006 to 2015
$3.4M
Development of an efficient cyanobacterial platform for heterologous expression and biosynthetic interrogations of natural products.R01GM118815 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GERWICK, LENA, GERWICK, WILLIAM HENRY · 2017 to 2020
$1.2M
NCI NIH HHS R01 CA108874NIGMS NIH HHS R01 GM107550NIGMS NIH HHS R01 GM118815
6 · The paper itself

Abstract

Cyanobacteria are major sources of oxygen, nitrogen, and carbon in nature. In addition to the importance of their primary metabolism, some cyanobacteria are prolific producers of unique and bioactive secondary metabolites. Chemical investigations of the cyanobacterial genus

Indexed as

Genome, BacterialGenomicsMetabolomeMetabolomicsBase CompositionCyanobacteriaGenes, BacterialMultigene FamilyNitrogen FixationOpen Reading FramesPhylogenybiosynthetic gene clustersgene cluster networkgenome comparisonheterocyst glycolipidstropical marine cyanobacteria

Identifiers

PMID28265051
PMCPMC5373345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.