Evidence map›Paper›PMID 28264991›Full record

ArticleJournal of bacteriology2017

GigA and GigB are Master Regulators of Antibiotic Resistance, Stress Responses, and Virulence in Acinetobacter baumannii.

Michael J Gebhardt, Howard A Shuman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. RpoS and the bacterial general stress response.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  5. Article
  6. Virulence Factors and Pathogenicity Mechanisms ofAntibiotics (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. TheFrontiers in microbiology · 2021
    Article
  14. Article
  15. Article
  16. Carbapenemases: TransformingBiomolecules · 2020
    Review
  17. Discovery of a Novel HypervirulentInfection and drug resistance · 2020
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael J GebhardtDepartment of Microbiology, University of Chicago, Chicago, Illinois, USA mgebhardt@uchicago.edu.ORCID http://orcid.org/0000-0002-1213-8408
Howard A ShumanDepartment of Microbiology, University of Chicago, Chicago, Illinois, USA.
University of Chicago · US

Funding

Regulation of stress resistance and virulence genes in Acinetobacter baumanniiR21AI115203 · NIAID · UNIVERSITY OF CHICAGO · PI SHUMAN, HOWARD A · 2015 to 2016
$423k
NIAID NIH HHS R21 AI115203
6 · The paper itself

Abstract

A critical component of bacterial pathogenesis is the ability of an invading organism to sense and adapt to the harsh environment imposed by the host's immune system. This is especially important for opportunistic pathogens, such as

Indexed as

Drug Resistance, BacterialGene Expression Regulation, BacterialGenes, RegulatorSignal TransductionStress, PhysiologicalAcinetobacter baumanniiGene Expression ProfilingGene Regulatory NetworksMetabolic Networks and PathwaysRegulonVirulenceAcinetobacter baumanniiantibiotic resistancenitrogen phosphotransferase systemsignal transductionstress response

Identifiers

PMID28264991
PMCPMC5405210
OpenAlexW2594246694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.