Evidence map›Paper›PMID 28264910›Full record

ReviewInfection and immunity2017

Expanding Role of Type II Secretion in Bacterial Pathogenesis and Beyond.

Nicholas P Cianciotto, Richard C White

Open access · bronzeAbstract readReview
In one paragraph

Review in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 1 pooled it
18.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 1 synthesis or guideline pooled it, 195 citations in OpenAlex.

  1. Genetic Fingerprint ofPathogens (Basel, Switzerland) · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
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  6. Article
  7. Mucin stimulates the growth ofMicrobiology (Reading, England) · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Molecular evolution and adaptations ofFrontiers in cellular and infection microbiology · 2026
    Review
  12. Article
  13. Article
  14. bioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. mBio · 2025
    Article
  18. Article
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  20. Genomic and phenotypic insights into Serratia interaction with plants from an ecological perspective.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicholas P CianciottoDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA n-cianciotto@northwestern.edu.
Richard C WhiteDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Northwestern University · US

Funding

TYPE II SECRETION AND LEGIONELLA PNEUMOPHILA INFECTIONR01AI043987 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 1999 to 2017
$4.8M
Virulence Mechanisms of the Emerging Pathogen Stenotrophomonas maltophiliaR21AI117082 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 2015 to 2016
$411k
NIAID NIH HHS R01 AI043987NIAID NIH HHS R21 AI117082
6 · The paper itself

Abstract

Type II secretion (T2S) is one means by which Gram-negative pathogens secrete proteins into the extracellular milieu and/or host organisms. Based upon recent genome sequencing, it is clear that T2S is largely restricted to the

Indexed as

Bacterial ProteinsGram-Negative BacteriaProtein TransportType II Secretion SystemsVirulence FactorsBacterial ProteinsType II Secretion SystemsVirulence Factorsanimal pathogensdegradative enzymeshuman pathogensLegionellaplant pathogensT2Stoxinstype II secretionVibrio

Identifiers

PMID28264910
PMCPMC5400843
OpenAlexW2592648241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.