Evidence map›Paper›PMID 28264867›Full record

ArticleCirculation research2017

A New Approach to PCSK9 Therapeutics.

Nan Wang, Alan R Tall

Abstract readComment
In one paragraph

Article in Circulation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Are RNA Therapies a Solid Foundation or a Frontier Yet to Be Conquered?International journal of molecular sciences · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nan WangFrom the Division of Molecular Medicine, Department of Medicine, Columbia University Medical Center, New York, NY. nw30@columbia.edu.
Alan R TallFrom the Division of Molecular Medicine, Department of Medicine, Columbia University Medical Center, New York, NY.

Funding

HDL, platelet progenitors, atherosclerosis and thrombosisR01HL118567 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WANG, NAN · 2014 to 2018
$2.0M
NHLBI NIH HHS R01 HL118567
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Proprotein Convertase 9RNAi TherapeuticsCholesterol, LDLProprotein ConvertasesCholesterol, LDLPCSK9 protein, humanProprotein Convertase 9Proprotein Convertases

Identifiers

PMID28264867
PMCPMC5848492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.