Evidence map›Paper›PMID 28264865›Full record

ArticleCancer discovery2017

Gatekeeper Mutations and Intratumoral Heterogeneity in

Elizabeth C Smyth, Irina S Babina, Nicholas C Turner

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cancer discovery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Synergic activity of FGFR2 and MEK inhibitors in the treatment of FGFR2-amplified cancers of unknown primary.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Intrahepatic Cholangiocarcinoma: State of the Art of FGFR Inhibitors.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Elizabeth C SmythDepartment of Gastrointestinal Oncology, Royal Marsden Hospital, London, United Kingdom.
Irina S BabinaMolecular Oncology, Breast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom.
Nicholas C TurnerMolecular Oncology, Breast Cancer Now Research Centre, The Institute of Cancer Research, London, United Kingdom. Nick.Turner@icr.ac.uk.
Breast Cancer Now · GBRoyal Marsden Hospital · GBRoyal Marsden NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

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Indexed as

Bile Duct NeoplasmsBile Ducts, IntrahepaticCholangiocarcinomaHumansLiver NeoplasmsMutationReceptor, Fibroblast Growth Factor, Type 2Receptor, Fibroblast Growth Factor, Type 2

Identifiers

PMID28264865
OpenAlexW2591695131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.