Evidence map›Paper›PMID 28264835›Full record

ArticleDevelopment (Cambridge, England)2017

IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.

Daisy Xin, Kasey J Christopher, Lewie Zeng, Yong Kong, Scott D Weatherbee

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Biliary, Renal, Neurological, and Skeletal syndrome in a Chinese boy.Pediatric nephrology (Berlin, Germany) · 2025
    Article
  6. The intraflagellar transport cycle.Nature reviews. Molecular cell biology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Intraflagellar Transport Proteins as Regulators of Primary Cilia Length.Frontiers in cell and developmental biology · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daisy XinDepartment of Genetics, Yale University, New Haven, CT 06520, USA.
Kasey J ChristopherDepartment of Genetics, Yale University, New Haven, CT 06520, USA.
Lewie ZengDepartment of Genetics, Yale University, New Haven, CT 06520, USA.
Yong KongDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
Scott D WeatherbeeDepartment of Genetics, Yale University, New Haven, CT 06520, USA scott.weatherbee@yale.edu.ORCID 0000-0002-0915-1329
Yale University · USW. M. Keck Foundation · US

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007499 · NIGMS · YALE UNIVERSITY · PI CARLSON, JOHN R, REINKE, VALERIE J · 1985 to 2022
$13.9M
GENETICS AND GENOMICS OF HUMAN DISEASET32HD007149 · NICHD · YALE UNIVERSITY · PI James P Noonan · 1985 to 2026
$8.2M
Center for Polycystic Kidney Disease Research at YaleP30DK090744 · NIDDK · YALE UNIVERSITY · PI CAPLAN, MICHAEL J. · 2010 to 2014
$5.6M
Skin Development Analysis in Mutant Mouse LinesR01AR059687 · NIAMS · YALE UNIVERSITY · PI WEATHERBEE, SCOTT DONALD · 2011 to 2015
$1.8M
NIAMS NIH HHS R01 AR059687NICHD NIH HHS T32 HD007149NIDDK NIH HHS P30 DK090744NIGMS NIH HHS T32 GM007499
6 · The paper itself

Abstract

Cilia are key regulators of animal development and depend on intraflagellar transport (IFT) proteins for their formation and function, yet the roles of individual IFT proteins remain unclear. We examined the

Indexed as

Body PatterningAdaptor Proteins, Signal TransducingAnimalsAxonemeCiliaCodon, NonsenseHedgehog ProteinsMiceMice, Inbred C57BLMicrotubulesNeural TubePhenotypePolydactylySignal TransductionVertebratesZinc Finger Protein GLI1Adaptor Proteins, Signal TransducingCodon, NonsenseHedgehog ProteinsZinc Finger Protein GLI1CiliaHedgehog signalingIFT56IFTBIntraflagellar transportMicrotubule structureTTC26

Identifiers

PMID28264835
PMCPMC5399663
OpenAlexW2591613012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.