Evidence map›Paper›PMID 28264700›Full record

SynthesisScandinavian journal of trauma, resuscitation and emergency medicine2017

The haemodynamic dilemma in emergency care: Is fluid responsiveness the answer? A systematic review.

Mohammed H Elwan, Ashraf Roshdy, Eman M Elsharkawy, Salah M Eltahan, Timothy J Coats

Abstract readSystematic Review
In one paragraph

Synthesis in Scandinavian journal of trauma, resuscitation and emergency medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The future of acute and emergency care.Future healthcare journal · 2021
    Article
  6. Emergency department non-invasive cardiac output study (EDNICO): an accuracy study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2020
    Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammed H ElwanDepartment of Emergency Medicine, Alexandria University, Alexandria, Egypt. mohammed.elwan@alexmed.edu.eg.
Ashraf RoshdyDepartment of Critical Care Medicine, Alexandria University, Alexandria, Egypt.
Eman M ElsharkawyDepartment of Cardiology, Alexandria University, Alexandria, Egypt.
Salah M EltahanDepartment of Cardiology, Alexandria University, Alexandria, Egypt.
Timothy J CoatsEmergency Medicine Academic Group, Department of Cardiovascular Sciences, University of Leicester, Level G Jarvis Building RMO, Infirmary Square, LE1 5WW, Leicester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluid therapy is a common and crucial treatment in the emergency department (ED). While fluid responsiveness seems to be a promising method to titrate fluid therapy, the evidence for its value in ED is unclear. We aim to synthesise the existing literature investigating fluid responsiveness in ED.

methodsMEDLINE, Embase and the Cochrane library were searched for relevant peer-reviewed studies published from 1946 to present.

resultsA total of 249 publications were retrieved of which 22 studies underwent full-text review and eight relevant studies were identified. Only 3 studies addressed clinical outcomes - including 2 randomised controlled trials and one feasibility study. Five articles evaluated the diagnostic accuracy of fluid responsiveness techniques in ED. Due to marked heterogeneity, it was not possible to combine results in a meta-analysis.

conclusionHigh quality, adequately powered outcome studies are still lacking, so the place of fluid responsiveness in ED remains undefined. Future studies should have standardisation of patient groups, the target response and the underpinning theoretic concept of fluid responsiveness. The value of a fluid responsiveness based fluid resuscitation protocol needs to be established in a clinical trial.

Indexed as

Emergency Service, HospitalFluid TherapyHemodynamicsAdultHumansCardiac outputEmergencyFluid responsivenessFluid therapyHaemodynamicsResuscitationShock

Identifiers

PMID28264700
PMCPMC5339987

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.