Evidence map›Paper›PMID 28264506›Full record

ReviewMolecules (Basel, Switzerland)2017

Plasma Membrane Na⁺-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy.

Yangzom D Bhutia, Jonathan J Kopel, John J Lawrence, Volker Neugebauer, Vadivel Ganapathy

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 78 citations in OpenAlex.

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  5. Cryo-EM structures reveal the HLife science alliance · 2025
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  15. A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth.Proceedings of the National Academy of Sciences of the United States of America · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yangzom D BhutiaDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. yangzom.d.bhutia@ttuhsc.edu.
Jonathan J KopelDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. jonathan.kopel@ttuhsc.edu.
John J LawrenceDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. john.lawrence@ttuhsc.edu.
Volker NeugebauerDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. volker.neugebauer@ttuhsc.edu.
Vadivel GanapathyDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. vadivel.ganapathy@ttuhsc.edu.
Texas Tech University · USTexas Tech University Health Sciences Center · US

Funding

PAIN, NOCICEPTION, AND THE AMYGDALAR01NS038261 · NINDS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI Volker Neugebauer, Igor Ponomarev · 1999 to 2026
$8.7M
Amygdala Serotonin Neurotransmission and Neuropathic PainR01NS081121 · NINDS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI GREEN, THOMAS ARTHUR, NEUGEBAUER, VOLKER · 2013 to 2017
$2.3M
6 · The paper itself

Abstract

SLC13A5 is a Na⁺-coupled transporter for citrate that is expressed in the plasma membrane of specific cell types in the liver, testis, and brain. It is an electrogenic transporter with a Na⁺:citrate

Indexed as

AnimalsBrainCitric AcidHumansInfantInfant, NewbornLiverMaleMutationSignal TransductionSpasms, InfantileSymportersTestisCitric AcidSLC13A5 protein, humanSymporterscholesterol synthesisCIC (SLC25A1)citrate transportercytoplasmic citratefatty acid synthesisGABAmitochondrial citrateNaCT (SLC13A5)neurotransmittersNMDA receptortricarboxylic acid cyclezinc

Identifiers

PMID28264506
PMCPMC6155422
OpenAlexW2593237849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.