Evidence map›Paper›PMID 28264502›Full record

ArticleSensors (Basel, Switzerland)2017

Rapid and Sensitive Lateral Flow Immunoassay Method for Procalcitonin (PCT) Based on Time-Resolved Immunochromatography.

Xiang-Yang Shao, Cong-Rong Wang, Chun-Mei Xie, Xian-Guo Wang, Rong-Liang Liang, Wei-Wen Xu

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
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  10. Microfluidic Paper-based Device for Medicinal Diagnosis.Current topics in medicinal chemistry · 2022
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiang-Yang ShaoInstitute of Antibody Engineering, State Key Laboratory of Organ Failure Research, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China. s1002297748@126.com.
Cong-Rong WangDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. cynthiawang21@hotmail.com.
Chun-Mei XieInstitute of Antibody Engineering, State Key Laboratory of Organ Failure Research, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China. plum225@126.com.
Xian-Guo WangR&D Center, DaRui Biotechnology Co., Ltd., Guangzhou 510655, China. 13250293361@163.com.
Rong-Liang LiangInstitute of Antibody Engineering, State Key Laboratory of Organ Failure Research, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China. liang.rongliang@163.com.
Wei-Wen XuInstitute of Antibody Engineering, State Key Laboratory of Organ Failure Research, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China. xuson@fimmu.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Procalcitonin (PCT) is a current, frequently-used marker for severe bacterial infection. The aim of this study was to develop a cost-effective detection kit for rapid quantitative and on-site detection of PCT. To develop the new PCT quantitative detecting kit, a double-antibody sandwich immunofluorescent assay was employed based on time-resolved immunofluorescent assay (TRFIA) combined with lateral flow immunoassay (LFIA). The performance of the new developed kit was evaluated in the aspects of linearity, precision, accuracy, and specificity. Two-hundred thirty-four serum samples were enrolled to carry out the comparison test. The new PCT quantitative detecting kit exhibited a higher sensitivity (0.08 ng/mL). The inter-assay coefficient of variation (CV) and the intra-assay CV were 5.4%-7.7% and 5.7%-13.4%, respectively. The recovery rates ranged from 93% to 105%. Furthermore, a high correlation (

Indexed as

Chromatography, AffinityBiomarkersCalcitoninCalcitonin Gene-Related PeptidePoint-of-Care SystemsProtein PrecursorsBiomarkersCalcitoninCalcitonin Gene-Related PeptideProtein Precursorsimmunochromatographyprocalcitonin (PCT)time-resolved

Identifiers

PMID28264502
PMCPMC5375766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.