Evidence map›Paper›PMID 28264448›Full record

ArticleMolecules (Basel, Switzerland)2017

Paeoniflorin Attenuates Cerebral Ischemia-Induced Injury by Regulating Ca

Yuqin Zhang, Lifei Qiao, Wen Xu, Xiaoying Wang, Huang Li, Wei Xu, Kedan Chu, Yu Lin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Extract ofInternational journal of molecular sciences · 2025
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  13. Review
  14. Role of CaFrontiers in molecular neuroscience · 2022
    Review
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  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuqin ZhangCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. zyqfj@hotmail.com.
Lifei QiaoCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. qlffjtcm@sina.com.
Wen XuCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. xwfjtcm@126.com.
Xiaoying WangCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. wxyfjtcm@sina.com.
Huang LiCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. lihuang3413@gmail.com.
Wei XuCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. xwfjlab@163.com.
Kedan ChuCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. chukedan@gmail.com.
Yu LinCollege of Pharmacy of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China. lyfjlab@163.com.
Fujian University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paeoniflorin (PF) is an active ingredient of Paeoniae Radix which possesses the neuroprotective effect. However, so far, the neuroprotective mechanism of PF has still not been fully uncovered. The Ca

Indexed as

AnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Cell ProliferationCells, CulturedCell SurvivalCyclic AMP Response Element-Binding ProteinDisease Models, AnimalGene Expression RegulationGlucosidesGlycosidesHippocampusInfarction, Middle Cerebral ArteryMonoterpenesNeuroprotective AgentsN-MethylaspartateCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Cyclic AMP Response Element-Binding ProteinGlucosidesGlycosidesMonoterpenesNeuroprotective AgentsN-MethylaspartatepeoniflorinCaMKIICREBischemic strokemiddle cerebral artery occlusionpaeoniflorin

Identifiers

PMID28264448
PMCPMC6155252
OpenAlexW2591786331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.