Evidence map›Paper›PMID 28264159›Full record

ArticleJournal of the American Chemical Society2017

Streamlined Synthesis and Assembly of a Hybrid Sensing Architecture with Solid Binding Proteins and Click Chemistry.

Brian J F Swift, Jared A Shadish, Cole A DeForest, François Baneyx

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian J F SwiftDepartment of Chemical Engineering, Box 351750, University of Washington , Seattle, Washington 98195, United States.
Jared A ShadishDepartment of Chemical Engineering, Box 351750, University of Washington , Seattle, Washington 98195, United States.
Cole A DeForestDepartment of Chemical Engineering, Box 351750, University of Washington , Seattle, Washington 98195, United States.
François BaneyxDepartment of Chemical Engineering, Box 351750, University of Washington , Seattle, Washington 98195, United States.ORCID 0000-0001-5596-7903

Funding

Project 3: Integrative Risk Assessment Methods for Engineered NanomaterialsU19ES019545 · NIEHS · UNIVERSITY OF WASHINGTON · PI KAVANAGH, TERRANCE J · 2010 to 2014
$5.6M
NIEHS NIH HHS U19 ES019545
6 · The paper itself

Abstract

Combining bioorthogonal chemistry with the use of proteins engineered with adhesive and morphogenetic solid-binding peptides is a promising route for synthesizing hybrid materials with the economy and efficiency of living systems. Using optical sensing of chloramphenicol as a proof of concept, we show here that a GFP variant engineered with zinc sulfide and silica-binding peptides on opposite sides of its β-barrel supports the fabrication of protein-capped ZnS:Mn nanocrystals that exhibit the combined emission signatures of organic and inorganic fluorophores. Conjugation of a chloramphenicol-specific DNA aptamer to the protein shell through strain-promoted azide-alkyne cycloaddition and spontaneous concentration of the resulting nanostructures onto SiO

Indexed as

Binding SitesChloramphenicolClick ChemistryDNAGreen Fluorescent ProteinsManganeseModels, MolecularParticle SizeProtein EngineeringSilicon DioxideSulfidesSurface PropertiesZinc CompoundsChloramphenicolDNAGreen Fluorescent ProteinsManganeseSilicon DioxideSulfidesZinc Compoundszinc sulfide

Identifiers

PMID28264159
PMCPMC8285024

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.