ArticlePloS one2017
mcr-1 identified in Avian Pathogenic Escherichia coli (APEC).
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 93 citations in OpenAlex.
- Co-existence of blaCTX-M and mcr-1 in avian pathogenic Escherichia coli in Southern Xinjiang: current status and antimicrobial resistance characteristics.Folia microbiologica · 2026Article
- Phenotypic and genotypic characterization ofHeliyon · 2024Article
- Genome-wide transcriptional profiling and functional analysis of long noncoding RNAs and mRNAs in chicken macrophages associated with the infection of avian pathogenic E. coli.BMC veterinary research · 2024Article
- Antimicrobial resistance of avian pathogenicVeterinary world · 2024Article
- First report of detection ofIranian journal of veterinary research · 2024Article
- Phenotypic and genotypic characterization of extended spectrum beta-lactamase producingOpen veterinary journal · 2024Article
- Mobile Colistin Resistance (Antibiotics (Basel, Switzerland) · 2023Review
- Farm to table: colistin resistance hitchhiking through food.Archives of microbiology · 2023Review
- Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens.Microbiology spectrum · 2022Article
- Phenotypic and Genotypic Screening of Colistin Resistance Associated with Emerging PathogenicVeterinary sciences · 2022Article
- Worldwide Prevalence ofPathogens (Basel, Switzerland) · 2022Review
- The Transcription RegulatorAnimals : an open access journal from MDPI · 2022Article
- Polyphenolic phytochemicals as natural feed additives to control bacterial pathogens in the chicken gut.Archives of microbiology · 2022Review
- Antimicrobial resistance in the globalized food chain: a One Health perspective applied to the poultry industry.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Review
- F Plasmid Lineages in Escherichia coli ST95: Implications for Host Range, Antibiotic Resistance, and Zoonoses.mSystems · 2022Article
- Evolution and implementation of One Health to control the dissemination of antibiotic-resistant bacteria and resistance genes: A review.Frontiers in cellular and infection microbiology · 2022Review
- Colistin Induces Resistance through Biofilm Formation, via IncreasedPathogens (Basel, Switzerland) · 2021Article
- Novel Small Molecule Growth Inhibitor Affecting Bacterial Outer Membrane Reduces Extraintestinal Pathogenic Escherichia coli (ExPEC) Infection in Avian Model.Microbiology spectrum · 2021Article
- Phenotypic and genotypic characterization of mcr-1-positive multidrug-resistant Escherichia coli ST93, ST117, ST156, ST10, and ST744 isolated from poultry in Poland.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Avian PathogenicPathogens (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial resistance associated with colistin has emerged as a significant concern worldwide threatening the use of one of the most important antimicrobials for treating human disease. Here, we examined a collection (n = 980) of Avian Pathogenic Escherichia coli (APEC) isolated from poultry with colibacillosis from the US and internationally for the presence of mcr-1 and mcr-2, genes known to encode colistin resistance. Included in the analysis was an additional set of avian fecal E. coli (AFEC) (n = 220) isolates from healthy birds for comparative analysis. The mcr-1 gene was detected in a total of 12 isolates recovered from diseased production birds from China and Egypt. No mcr genes were detected in the healthy fecal isolates. The full mcr-1 gene from positive isolates was sequenced using specifically designed primers and were compared with sequences currently described in NCBI. mcr-1 positive isolates were also assessed for phenotypic colistin resistance and extended spectrum beta lactam phenotypes and genotypes. This study has identified mcr-1 in APEC isolates dating back to at least 2010 and suggests that animal husbandry practices could result in a potential source of resistance to the human food chain in countries where application of colistin in animal health is practiced.
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Registered trials
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