Evidence map›Paper›PMID 28263553›Full record

ArticleACS applied materials & interfaces2017

In Situ-Forming Polyamidoamine Dendrimer Hydrogels with Tunable Properties Prepared via Aza-Michael Addition Reaction.

Juan Wang, Hongliang He, Remy C Cooper, Hu Yang

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Adaptive PEG Bis-dendron Hydrogels with Tunable Mechanics and Bioactivity.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  2. Dendrimers-based Hydrogels and Nanogels for Drug Delivery.Current pharmaceutical biotechnology · 2026
    Review
  3. Article
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  9. Nanocarrier-hydrogel composite delivery systems for precision drug release.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022
    Review
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  19. Dendrimers for Ocular Drug Delivery.Canadian journal of chemistry · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan WangDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University , Richmond, Virginia 23219, United States.
Hongliang HeDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University , Richmond, Virginia 23219, United States.
Remy C CooperDepartment of Biomedical Engineering, Virginia Commonwealth University , Richmond, Virginia 23284, United States.
Hu YangDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University , Richmond, Virginia 23219, United States.ORCID http://orcid.org/0000-0003-3030-004X

Funding

Hybrid Nanoparticles for GlaucomaR01EY024072 · NEI · VIRGINIA COMMONWEALTH UNIVERSITY · PI KOMPELLA, UDAY B, YANG, HU · 2014 to 2016
$1.3M
NEI NIH HHS R01 EY024072
6 · The paper itself

Abstract

In this work, we describe synthesis and characterization of novel in situ-forming polyamidoamine (PAMAM) dendrimer hydrogels (DHs) with tunable properties prepared via highly efficient aza-Michael addition reaction. PAMAM dendrimer G5 was chosen as the underlying core and functionalized with various degrees of acetylation using acetic anhydride. The nucleophilic amines on the dendrimer surface reacted with α, β-unsaturated ester in acrylate groups of polyethylene glycol diacrylate (PEG-DA, M

Indexed as

DendrimersHydrogelsPolyaminesPolyethylene GlycolsTissue EngineeringDendrimersHydrogelsPoly(amidoamine)PolyaminesPolyethylene Glycolsclick chemistrydendrimerinjectable hydrogelin situ forminglocalized chemotherapy

Identifiers

PMID28263553
PMCPMC5818279

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.