Evidence map›Paper›PMID 28263389›Full record

ArticleCancer2017

Second opinions from urologists for prostate cancer: Who gets them, why, and their link to treatment.

Archana Radhakrishnan, David Grande, Nandita Mitra, Justin Bekelman, Christian Stillson, Craig Evan Pollack

Abstract read
In one paragraph

Article in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Second opinions in medical oncology.BMC palliative care · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Archana RadhakrishnanDivision of General Internal Medicine, Johns Hopkins University, Baltimore, Maryland.
David GrandeDivision of General Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Nandita MitraDepartment of Biostatistics and Epidemiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Justin BekelmanDepartment of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Christian StillsonDivision of General Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Craig Evan PollackDivision of General Internal Medicine, Johns Hopkins University, Baltimore, Maryland.
Hospital of the University of Pennsylvania · USJohns Hopkins University · US

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Robert H. Vonderheide · 1985 to 2026
$222.3M
BEHAVIORAL RESEARCH IN HEART &VASCULAR DISEASET32HL007180 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MARUTHUR, NISA M · 1985 to 2020
$11.4M
Research Traiing/Education CoreP60MD006900 · NIMHD · UNIVERSITY OF PENNSYLVANIA · PI GLANZ, KAREN · 2012 to 2016
$6.6M
Effectiveness of Radiotherapy for Prostate CancerK07CA163616 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BEKELMAN, JUSTIN · 2012 to 2016
$875k
A Network Analytic Approach to Modeling Variation in Prostate Cancer CareK07CA151910 · NCI · JOHNS HOPKINS UNIVERSITY · PI POLLACK, CRAIG EVAN · 2011 to 2015
$780k
NCI NIH HHS K07 CA151910NCI NIH HHS K07 CA163616NCI NIH HHS P30 CA016520NHLBI NIH HHS T32 HL007180NIMHD NIH HHS P60 MD006900
6 · The paper itself

Abstract

backgroundCancer patients are encouraged to obtain second opinions before starting treatment. Little is known about men with localized prostate cancer who seek second opinions, the reasons why, and the association with treatment and quality of care.

methodsWe surveyed men who were diagnosed with localized prostate cancer in the greater Philadelphia area from 2012 to 2014. Men were asked if they obtained a second opinion from a urologist, and the reasons why. We used multivariable logistic regression models to evaluate the relationship between second opinions and definitive prostate cancer treatment and perceived quality of care.

resultsA total of 2386 men responded to the survey (adjusted response rate, 51.1%). After applying exclusion criteria, the final analytic cohort included 2365 respondents. Of these, 40% obtained second opinions, most commonly because they wanted more information about their cancer (50.8%) and wanted to be seen by the best doctor (46.3%). Overall, obtaining second opinions was not associated with definitive treatment or perceived quality of cancer care. Men who sought second opinions because they were dissatisfied with their initial urologist were less likely to receive definitive treatment (odds ratio, 0.49; 95% confidence interval, 0.32-0.73), and men who wanted more information about treatment were less likely to report excellent quality of cancer care (odds ratio, 0.70; 95% confidence interval, 0.49-0.99) compared with men who did not receive a second opinion.

conclusionsAlthough a large proportion of men with localized prostate cancer obtained a second opinion, the reasons for doing so were not associated with treatment choice or perceived quality of cancer care. Future study is needed to determine when second opinions contribute to increasing the value of cancer care. Cancer 2017;123:1027-34. © 2016 American Cancer Society.

Indexed as

Referral and ConsultationUrologistsAdultAgedAged, 80 and overClinical Decision-MakingDisease ManagementHumansMaleMiddle AgedNeoplasm GradingNeoplasm StagingOdds RatioPatient SatisfactionPennsylvaniaPractice Patterns, Physicians'prostate cancerquality of health caresecond opinionspecialiststreatment

Identifiers

PMID28263389
PMCPMC5341133
OpenAlexW2556249364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.