ArticleJournal of the American Geriatrics Society2017
Association Between Preoperative Malnutrition and Postoperative Delirium After Hip Fracture Surgery in Older Adults.
Article in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 76 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Perioperative Nutritional Intervention on Perioperative Outcomes of Elderly Patients Having Hip Fracture Surgery: A Randomized Control Trial
Effect of Multicomponent Prehabilitation on Early and Long-term Outcomes in Elderly Patients With Frailty After Digestive Surgery for Cancer: A Randomized-controlled Study
Who cites it
76 citing papers in PubMed, 5 syntheses or guidelines pooled it, 143 citations in OpenAlex.
- Malnutrition-Related Health Outcomes in Older Adults with Hip Fractures: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Predisposing and Precipitating Factors Associated With Delirium: A Systematic Review.JAMA network open · 2023Pooled it
- Micronutrient Deficiency and Its Potential Role in Delirium Onset in Older Adults: A Systematic Review.The journal of nutrition, health & aging · 2023Pooled it
- Risk factors for postoperative delirium in geriatric patients with hip fracture: A systematic review and meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- Pooled it
- Economic evaluation of an extended nutritional intervention in older Australian hospitalized patients: a randomized controlled trial.BMC geriatrics · 2018Trial
- Feasibility and candidate risk factors for postoperative delirium in older ward patients: a prospective pilot study.BMC anesthesiology · 2026Observational
- Malnutrition as an independent risk factor for incident delirium in cohort of older adults receiving domiciliary care services.GeroScience · 2026Article
- Association of prognostic nutritional index with mortality in patients with sepsis-associated delirium: a retrospective MIMIC-IV study.BMC neurology · 2026Article
- Impact of CGA and Surgical Risk Calculator before elective cancer surgery on postoperative delirium in elderly patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Validating Mini Nutritional Assessment-Short Form thresholds for postoperative mortality and complications in geriatric hip fracture patients with compromised nutritional status.Joint diseases and related surgery · 2026Article
- Effects of Intraoperative Prone Versus Supine Positioning on Postoperative Delirium.Geriatrics (Basel, Switzerland) · 2026Article
- Recommendations from the European interdisciplinary council on ageing on physical activity and diet for mental health conditions in older adults.Aging clinical and experimental research · 2026Review
- Nutrition-related clinical laboratory indicators in perioperative management of geriatric hip fractures: a narrative review from risk stratification to precision intervention.Frontiers in nutrition · 2026Review
- Association Between Preoperative Malnutrition Assessed by the Controlling Nutritional Status (CONUT) Score and Postoperative Delirium in Elderly Patients with Hip Fractures: A Retrospective Cohort Study.International journal of general medicine · 2026Article
- Postoperative delirium in orthopedic patients - identifying contributing factors and therapeutic strategies: A review.Medicine · 2025Review
- Development and validation of a delirium prediction model for hospitalized older medical patients: a prospective cohort study.BMC geriatrics · 2025Article
- Article
- A nomogram model to predict postoperative delirium in esophageal cancer patients undergoing esophagectomy.BMC cancer · 2025Article
- Association Between Low Omega-6 Polyunsaturated Fatty Acid Levels and the Development of Delirium in the Coronary Intensive Care Unit.Nutrients · 2025Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
objectivesTo determine whether poor nutritional status can predict postoperative delirium in elderly adults undergoing hip fracture surgery.
designProspective observational cohort study.
settingItalian orthogeriatric unit.
participantsIndividuals aged 70 and older (mean age 84.0 ± 6.6, 74.5% female) consecutively admitted for surgical repair of a proximal femur fracture between September 2012 and April 2016 (N = 415). MEASUREMENTS: Participants underwent a comprehensive geriatric assessment including nutritional status, which was evaluated using the Mini Nutritional Assessment Short Form (MNA-SF). The MNA-SF-based three-class stratification was tested using multivariable logistic regression to assess its role in predicting postoperative delirium (outcome).
resultsSeventy-eight malnourished individuals (MNA-SF score 0-7), 185 at risk of malnutrition (MNA-SF score 8-11), and 152 who were well nourished (MNA-SF score 12-14) were compared. On average, individuals with poor nutritional status were more disabled and more cognitively impaired than those who were well nourished and those at risk of malnutrition. Moreover, those who were malnourished were more likely to have postoperative delirium. Multivariate regression analysis adjusted for age, sex, comorbidity, functional impairment, preoperative cognitive status, and American Society of Anesthesiologists score showed that those who were at risk of malnutrition (odds ratio (OR) = 2.42, 95% confidence interval (CI) = 1.29-4.53) and those who were overtly malnourished (OR = 2.98, 95% CI = 1.43-6.19) were more likely to develop postoperative delirium.
conclusionThis is the first study in a Western population showing that risk of malnutrition and overt malnutrition, as assessed using the MNA-SF, are independent predictors of postoperative delirium. Accordingly, nutritional status should be assessed in individuals with hip fracture before surgery to determine risk of developing delirium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.