ArticleJournal of medical radiation sciences2017
Initial experience with intra-fraction motion monitoring using Calypso guided volumetric modulated arc therapy for definitive prostate cancer treatment.
Article in Journal of medical radiation sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Phase II trial of high dose stereotactic body radiation therapy for lymph node oligometastases.Clinical & experimental metastasis · 2020Trial
- Application of Photon-Derived Worst-Case Robustness Criteria to Proton Therapy Planning.International journal of particle therapy · 2025Article
- Article
- Prostate cancer radiotherapy and incidental testicular irradiation: Impact on gonadal function.Clinical and translational radiation oncology · 2023Article
- Evaluation of internal margins for prostate for step and shoot intensity-modulated radiation therapy and volumetric modulated arc therapy using different margin formulas.Journal of applied clinical medical physics · 2022Article
- Retrospective analysis of MV-kV imaging-based fiducial tracking in prostate SBRT treatment.Journal of applied clinical medical physics · 2022Article
- Special stereotactic radiotherapy techniques: procedures and equipment for treatment simulation and dose delivery.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022Review
- Intrafraction Prostate Motion Management During Dose-Escalated Linac-Based Stereotactic Body Radiation Therapy.Frontiers in oncology · 2022Article
- Simulation of an HDR "Boost" with Stereotactic Proton versus Photon Therapy in Prostate Cancer: A Dosimetric Feasibility Study.International journal of particle therapy · 2021Article
- A study of the clinical, treatment planning and dosimetric feasibility of dose painting in external beam radiotherapy of prostate cancer.Physics and imaging in radiation oncology · 2020Article
- Predicting real-time 3D deformation field maps (DFM) based on volumetric cine MRI (VC-MRI) and artificial neural networks for on-board 4D target tracking: a feasibility study.Physics in medicine and biology · 2019Article
- Initial experience with intra-fraction motion monitoring using Calypso guided volumetric modulated arc therapy for definitive prostate cancer treatment.Journal of medical radiation sciences · 2017Article
- Triggered kV Imaging During Spine SBRT for Intrafraction Motion Management.Technology in cancer research & treatmentArticle
- Evaluating the potential benefit of reduced planning target volume margins for low and intermediate risk patients with prostate cancer using real-time electromagnetic tracking.Advances in radiation oncologyArticle
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionAccurate delivery of radiation while reducing dose to organs at risk is essential in prostate treatment. The Calypso motion management system detects and corrects both inter- and intra-fraction motion which offers potential benefits over standard alignment to fiducial markers. The aims of this study were to implement Calypso with Dynamic Edge™ gating and to assess both the motion seen, and interventions required.
methodsAn implementation group was formed which assessed changes needed to standard workflows. Three patients had Calypso beacons inserted into their prostate. All patients were treated using volumetric modulated arc therapy to a dose of 80 Gy in 40 fractions. Standard inter-fraction motion correction using either kilovoltage (kV) orthogonal paired imaging or cone beam computed tomography (CBCT) image-guided radiotherapy techniques, were used along with the Calypso system to compare accuracy. A gating threshold of >0.5 cm was used during treatment. Workflow variations along with inter- and intra-fraction motion and interventions required were assessed.
resultsA total of 116 fractions were treated using Calypso with Dynamic Edge™ gating. There was a strong concordance between aligning beacons using kV orthogonal imaging or CBCT and Calypso (mean variation ≤0.06 cm). The mean intra-fraction motion detected was ≤0.2 cm in all directions with the largest motion recorded being 2.2 cm in the left direction while the treatment beam was off. Prostate rotation was largest in the pitch direction and 28 fractions exceeded the 10° tolerance. A total of 78 couch shift corrections of ≥0.3 cm were required, usually following standard imaging, and before treatment starting. Three gating events due to intra-fraction motion occurred during treatment.
conclusionsIntra-fraction motion monitoring with Calypso was successfully implemented. Greatest movement was seen between time of standard imaging and treatment starting with more than half the treatments requiring a ≥0.3 cm adjustment. This would not have been detected without intra-fraction monitoring.
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