ArticleHuman brain mapping2017
Age differences in the motor control of speech: An fMRI study of healthy aging.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Translation of task-evoked negative BOLD response into aging and Alzheimer's disease: a systematic review of the current literature.Journal of translational medicine · 2025Pooled it
- Speech changes in old age: Methodological considerations for speech-based discrimination of healthy ageing and Alzheimer's disease.International journal of language & communication disordersPooled it
- Motor speech markers of Alzheimer's risk.GeroScience · 2026Article
- Cerebellum and Aging: Update and Challenges.Aging and disease · 2024Review
- The characteristics and reproducibility of motor speech functional neuroimaging in healthy controls.Frontiers in human neuroscience · 2024Article
- Differential effects of ageing on the neural processing of speech and singing production.Frontiers in aging neuroscience · 2023Article
- Aging-related decline in the neuromotor control of speech production: current and future.Frontiers in aging neuroscience · 2023Article
- How the motor system copes with aging: a quantitative meta-analysis of the effect of aging on motor function control.Communications biology · 2022Review
- Verbal Training Induces Enhanced Functional Connectivity in Japanese Healthy Elderly Population.Frontiers in human neuroscience · 2022Article
- Attention in post-lexical processes of utterance production: Dual-task cost in younger and older adults.Quarterly journal of experimental psychology (2006) · 2021Article
- Sigma-Lognormal Modeling of Speech.Cognitive computation · 2021Article
- Lexical frequency affects functional activation and accuracy in picture naming among older and younger adults.Psychology and aging · 2020Article
- Functional Connectivity of Successful Picture-Naming: Age-Specific Organization and the Effect of Engaging in Stimulating Activities.Frontiers in aging neuroscience · 2020Article
- Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition.Neurobiology of language (Cambridge, Mass.) · 2020Article
- Model-Based and Model-Free Analyses of the Neural Correlates of Tongue Movements.Frontiers in neuroscience · 2020Article
- Behavioral and neural correlates of normal aging effects on motor preparatory mechanisms of speech production and limb movement.Experimental brain research · 2019Article
- Dimensional Complexity of the Resting Brain in Healthy Aging, Using a Normalized MPSE.Frontiers in human neuroscience · 2018Article
- Aging and Sex Influence Cortical Auditory-Motor Integration for Speech Control.Frontiers in neuroscience · 2018Article
- Motor-Speech Performance in Very Old Speakers: Associations With Physio-Anatomical and Cognitive-Linguistic Factors.International journal of language & communication disordersArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Healthy aging is associated with a decline in cognitive, executive, and motor processes that are concomitant with changes in brain activation patterns, particularly at high complexity levels. While speech production relies on all these processes, and is known to decline with age, the mechanisms that underlie these changes remain poorly understood, despite the importance of communication on everyday life. In this cross-sectional group study, we investigated age differences in the neuromotor control of speech production by combining behavioral and functional magnetic resonance imaging (fMRI) data. Twenty-seven healthy adults underwent fMRI while performing a speech production task consisting in the articulation of nonwords of different sequential and motor complexity. Results demonstrate strong age differences in movement time (MT), with longer and more variable MT in older adults. The fMRI results revealed extensive age differences in the relationship between BOLD signal and MT, within and outside the sensorimotor system. Moreover, age differences were also found in relation to sequential complexity within the motor and attentional systems, reflecting both compensatory and de-differentiation mechanisms. At very high complexity level (high motor complexity and high sequence complexity), age differences were found in both MT data and BOLD response, which increased in several sensorimotor and executive control areas. Together, these results suggest that aging of motor and executive control mechanisms may contribute to age differences in speech production. These findings highlight the importance of studying functionally relevant behavior such as speech to understand the mechanisms of human brain aging. Hum Brain Mapp 38:2751-2771, 2017. © 2017 Wiley Periodicals, Inc.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.