ArticleScientific reports2017
Diagnostic implication of fibrin degradation products and D-dimer in aortic dissection.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Diagnostic strategies for suspected acute aortic syndrome: systematic review, meta-analysis, decision-analytic modelling and value of information analysis.Health technology assessment (Winchester, England) · 2025Pooled it
- Diagnostic accuracy of alternative biomarkers for acute aortic syndrome: a systematic review.Emergency medicine journal : EMJ · 2024Pooled it
- The diagnostic value of D-dimer in acute aortic dissection: a meta-analysis.Journal of cardiothoracic surgery · 2021Pooled it
- Trial
- Integrated biomarker model based on cTnI, BNP, and D-dimer for early risk stratification in acute aortic dissection.Frontiers in cardiovascular medicine · 2026Article
- The Role of Biomarkers and Clinical Prediction Tools in the Diagnosis of Acute Aortic Syndromes: A Literature-Based Review.Medicina (Kaunas, Lithuania) · 2025Review
- Exploring Biomarkers to Predict Thrombogenic Risk in Pregnancy.Journal of clinical medicine · 2025Article
- Endovascular reperfusion followed by delayed open aortic repair in stable acute type A aortic dissection with malperfusion syndrome: a single-center experience.Frontiers in medicine · 2025Article
- Article
- The Impact of Cardiovascular Disease Gene Polymorphism and Interaction with Homocysteine on Deep Vein Thrombosis.ACS omega · 2024Article
- Risk factors of atrial fibrillation complicated with cognitive impairment and the relationship between cardiac function parameters and the degree of cognitive impairment.Clinics (Sao Paulo, Brazil) · 2024Article
- The association of coagulation indicators with in-hospital acute kidney injury and malignant events of patients with acute aortic dissection: a retrospective cohort study.Journal of thoracic disease · 2023Article
- Current Understanding of Aortic Dissection.Life (Basel, Switzerland) · 2022Review
- Diagnostic Value of D-Dimer and INR in Patients Suspected to Have Prosthetic Valve Dysfunction.Brazilian journal of cardiovascular surgery · 2022Article
- Emergency Cardiac Surgery for Acute Type A Aortic Dissection on Apixaban.Anatolian journal of cardiology · 2022Article
- Neutrophil to lymphocyte ratio and fibrinogen values in predicting patients with type B aortic dissection.Scientific reports · 2021Article
- Aortic Dissection: A Review of the Pathophysiology, Management and Prospective Advances.Current cardiology reviews · 2021Review
- Coagulation parameters are associated with the prognosis of immunoglobulin a nephropathy: a retrospective study.BMC nephrology · 2020Article
- Fibrin Breakdown Assay.Bio-protocol · 2020Article
- Article
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10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibrin degradation products (FDP) and D-dimer have been considered to be involved in many vascular diseases. In this study we aimed to explore the diagnostic implication of FDP and D-dimer in aortic dissection patients. 202 aortic dissection patients were collected as the case group, 150 patients with other cardiovascular diseases, including myocardial infarction (MI, n = 45), pulmonary infarction (n = 51) and abdominal aortic aneurysm (n = 54) were collected as non-dissection group, and 27 healthy people were in the blank control group. The FDP and D-dimer levels were detected with immune nephelometry. Logist regression analysis was performed to evaluate the influence of FDP and D-dimer for the aortic dissection patients. ROC curve was used to determine the diagnostic value of FDP and D-dimer. The FDP and D-dimer levels were significantly higher in aortic dissection patients than in non-dissection patients and the healthy controls. FDP and D-dimer were both the risk factors for patients with aortic dissection. From the ROC analysis, diagnostic value of FDP and D-dimer were not high to distinguish aortic dissection patients from the non-dissection patients. However FDP and D-dimer could be valuable diagnostic marker to differentiate aortic dissection patients and healthy controls with both AUC 0.863.
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