Evidence map›Paper›PMID 28262641›Full record

ArticleJournal of vestibular research : equilibrium & orientation2016

Vestibular paroxysmia: Diagnostic criteria.

Michael Strupp, Jose A Lopez-Escamez, Ji-Soo Kim, Dominik Straumann, Joanna C Jen, John Carey, Alexandre Bisdorff, Thomas Brandt

Open access · greenAbstract read
In one paragraph

Article in Journal of vestibular research : equilibrium & orientation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 1 synthesis or guideline pooled it, 223 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  9. Vestibular Dysfunction and Binocular Vision Impairment: A New Clinical Perspective.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  10. Article
  11. Article
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  13. [The SCD diagnostic strategy, procedure and pathway for episodic vestibular syndrome].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Michael StruppDepartment of Neurology and German Center for Vertigo and Balance Disorders, University Hospital Munich, University of Munich, Germany.
Jose A Lopez-EscamezOtology and Neurotology Group CTS495, Department of Genomic Medicine - Centre for Genomics and Oncology Research - Pfizer/Universidad de Granada/Junta de Andalucía (GENyO), PTS, Granada and Department of Otolaryngology, University Hospital Granada, Spain.
Ji-Soo KimDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, South Korea.
Dominik StraumannDepartment of Neurology, University Hospital Zurich, University of Zurich, Switzerland.
Joanna C JenDepartment of Neurology & Neurobiology, University of California, Los Angeles, CA, USA.
John CareyDepartment of Otorhinolaryngology, Johns Hopkins University School of Medicine, Baltimore, USA.
Alexandre BisdorffDepartment of Neurology, Centre Hospitalier Emile Mayrisch, Esch, Luxemburg.
Thomas BrandtDepartment of Neurology and German Center for Vertigo and Balance Disorders, University Hospital Munich, University of Munich, Germany.
Centre hospitalier Emile Roux · FRJohns Hopkins University · USPfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research · ESSeoul National University Bundang Hospital · KRUniversity of California, Los Angeles · USUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper describes the diagnostic criteria for vestibular paroxysmia (VP) as defined by the Classification Committee of the Bárány Society. The diagnosis of VP is mainly based on the patient history and requires: A) at least ten attacks of spontaneous spinning or non-spinning vertigo; B) duration less than 1 minute; C) stereotyped phenomenology in a particular patient; D) response to a treatment with carbamazepine/oxcarbazepine; and F) not better accounted for by another diagnosis. Probable VP is defined as follows: A) at least five attacks of spinning or non-spinning vertigo; B) duration less than 5 minutes; C) spontaneous occurrence or provoked by certain head-movements; D) stereotyped phenomenology in a particular patient; E) not better accounted for by another diagnosis.Ephaptic discharges in the proximal part of the 8th cranial nerve, which is covered by oligodendrocytes, are the assumed mechanism. Important differential diagnoses are Menière's disease, vestibular migraine, benign paroxysmal positional vertigo, epileptic vestibular aura, paroxysmal brainstem attacks (in multiple sclerosis or after brainstem stroke), superior canal dehiscence syndrome, perilymph fistula, transient ischemic attacks and panic attacks. Current areas of uncertainty in the diagnosis of VP are: a) MRI findings of vascular compression which are not diagnostic of the disease or predictive for the affected side because they are also observed in about 30% of healthy asymptomatic subjects; and b) response to treatment with carbamazepine/oxcarbazepine supports the diagnosis but there are so far no randomized controlled trials for treatment of VP.

Indexed as

Benign Paroxysmal Positional VertigoCarbamazepineDiagnosis, DifferentialFemaleHead MovementsHumansMagnetic Resonance ImagingMaleOtologic Surgical ProceduresOxcarbazepinePrevalenceVertigoVestibular DiseasesVestibular Function TestsVestibulocochlear NerveCarbamazepineOxcarbazepineattacksdizzinessICVDneurovascular compressionVertigo

Identifiers

PMID28262641
PMCPMC9249278
OpenAlexW2580661229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.