Evidence map›Paper›PMID 28261962›Full record

ReviewInternational wound journal2017

An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing.

Calver Pang, Amel Ibrahim, Neil W Bulstrode, Patrizia Ferretti

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International wound journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Calver PangDepartment of Surgery Surgical Research, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Amel IbrahimStem Cells and Regenerative Medicine Section, UCL GOS Institute of Child Health, University College London, London, UK.
Neil W BulstrodeStem Cells and Regenerative Medicine Section, UCL GOS Institute of Child Health, University College London, London, UK.
Patrizia FerrettiStem Cells and Regenerative Medicine Section, UCL GOS Institute of Child Health, University College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global burden of disease associated with wounds is an increasingly significant public health concern. Current treatments are often expensive, time-consuming and limited in their efficacy in chronic wounds. The challenge of overcoming current barriers associated with wound care requires innovative management techniques. Regenerative medicine is an emerging field of research that focuses on the repair, replacement or regeneration of cells, tissues or organs to restore impaired function. This article provides an overview of the pathophysiology of wound healing and reviews the latest evidence on the application of the principal components of regenerative medicine (growth factors, stem cell transplantation, biomaterials and tissue engineering) as therapeutic targets. Improved knowledge and understanding of the pathophysiology of wound healing has pointed to new therapeutic targets. Regenerative medicine has the potential to underpin the design of specific target therapies in acute and chronic wound healing. This personalised approach could eventually reduce the burden of disease associated with wound healing. Further evidence is required in the form of large animal studies and clinical trials to assess long-term efficacy and safety of these new treatments.

Indexed as

Biocompatible MaterialsHumansIntercellular Signaling Peptides and ProteinsRegenerationRegenerative MedicineSkinStem Cell TransplantationTissue EngineeringWound HealingBiocompatible MaterialsIntercellular Signaling Peptides and ProteinsBiomaterialsGrowth factorsRegenerative medicineStem cellsTissue engineeringWound healing

Identifiers

PMID28261962
PMCPMC7949790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.