ArticleMagnetic resonance in medicine2017
In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1-
Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Hyperpolarized MRI in Oncology-A Review of Clinical Studies and Evaluation of Preclinical Liver Studies.NMR in biomedicine · 2026Review
- Stable electron-irradiated [1-Science advances · 2025Article
- Analyses of mitochondrial metabolism in diseases: a review onRSC advances · 2024Review
- Hyperpolarized [1-ACS sensors · 2023Article
- Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities.Liver international : official journal of the International Association for the Study of the Liver · 2022Review
- HyperpolarizedAntioxidants & redox signaling · 2022Review
- Co-Polarized [1-ACS sensors · 2021Article
- Non-Invasive Analysis of Human Liver Metabolism by Magnetic Resonance Spectroscopy.Metabolites · 2021Review
- Non-invasive assessment of telomere maintenance mechanisms in brain tumors.Nature communications · 2021Article
- Simultaneous Assessment of Intracellular and Extracellular pH Using Hyperpolarized [1-Analytical chemistry · 2020Article
- Computational pipeline for estimation of small-molecule T1 relaxation times.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2020Article
- HyperpolarisedMagma (New York, N.Y.) · 2020Review
- Metabolism of hyperpolarizedNMR in biomedicine · 2019Article
- HyperpolarizedNeoplasia (New York, N.Y.) · 2019Review
- Hyperpolarized [1-Physiological reports · 2018Article
- Late-stage deuteration ofChemical communications (Cambridge, England) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
purposeThe intracellular lactate to pyruvate concentration ratio is a commonly used tissue assay biomarker of redox, being proportional to free cytosolic [NADH]/[NAD
methodsAnimal experiments were conducted to measure in vivo metabolism at baseline and after ethanol infusion. A solution of 80-mM hyperpolarized [1-
resultsIn vivo rat liver spectra showed peaks from [1-
conclusionA method to measure in vivo tissue redox using hyperpolarized [1-
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.