Evidence map›Paper›PMID 28261683›Full record

ArticleInvestigative and clinical urology2017

Botox combined with myofascial release physical therapy as a treatment for myofascial pelvic pain.

Gabriela E Halder, Lauren Scott, Allison Wyman, Nelsi Mora, Branko Miladinovic, Renee Bassaly, Lennox Hoyte

2 registry-linked trialsOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Investigative and clinical urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05750212 recruitingnot on this mapstarted 2023, after this paper: background citation

Musculoskeletal and Pelvic Floor Health in Female Chronic Overlapping Pelvic Pain Conditions (The MSK-PELVIC Study)

TypeobservationalSponsorLoyola UniversityRan2023 to 2025Enrolled208ConditionsChronic Pelvic Pain SyndromeArmsTone, Tenderness, Contraction, Relaxation, Electromyography
NCT05851742 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Myofascial Release With and Without Electrical Stimulation on Pain and Functionality in Women With Chronic Pelvic Pain

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled24ConditionsChronic Pelvic Pain, Myofascial Trigger Point PainArmsTENS, Myofascial trigger point release
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

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  11. Instrumental assessment of physiotherapy and onabolulinumtoxin-A on cervical and headache parameters in chronic migraine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Observational
  12. Article
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  14. Botulinum injections for myofascial pelvic pain.International urogynecology journal · 2021
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gabriela E HalderDepartment of Obstetrics and Gynecology, University of South Florida, Tampa, FL, USA.
Lauren ScottDepartment of Female Pelvic Floor Medicine and Reconstructive Surgery, University of South Florida, Tampa, FL, USA.
Allison WymanDepartment of Female Pelvic Floor Medicine and Reconstructive Surgery, University of South Florida, Tampa, FL, USA.
Nelsi MoraMorsani School of Medicine, University of South Florida, Tampa, FL, USA.
Branko MiladinovicCenter for Comparative Effectiveness Research and Evidence-based Medicine, University of South Florida, Tampa, FL, USA.
Renee BassalyDepartment of Female Pelvic Floor Medicine and Reconstructive Surgery, University of South Florida, Tampa, FL, USA.
Lennox HoyteDepartment of Female Pelvic Floor Medicine and Reconstructive Surgery, University of South Florida, Tampa, FL, USA.
University of South Florida · USInstitute for Female Pelvic Medicine and Reconstructive Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the effects of combined onabotulinumtoxinA (Botox) injections and myofascial release physical therapy on myofascial pelvic pain (MFPP) by comparing pre- and posttreatment average pelvic pain scores, trigger points, and patient self-reported pelvic pain. Secondary outcomes were to examine posttreatment complications and determine demographic differences between patients with/without an improvement in pain. MATERIALS AND

methodsThis was an Institutional Review Board approved retrospective case series on women over 18 years with MFPP who received Botox and physical therapy between July 2006 and November 2014. Presence of trigger points and pelvic pain scores were determined by digital palpation of the iliococcygeus, puborectalis, obturator internus, and rectus muscles. Average pelvic pain scores (0-10) reflected an average of the scores obtained from palpation of each muscle. Self-reported improvement in pain was recorded as yes/no.

resultsFifty women met the inclusion/exclusion criteria. Posttreatment, patients had lower average pelvic pain scores (3.7±4.0 vs. 6.4±1.8, p=0.005), and fewer trigger points (44% vs. 100%, p<0.001). Fifty-eight percent of patients (95% confidence interval, 44-72) noted an improvement in self-reported pain. Patients most likely to report no improvement in pain had chronic bowel disorders, while those most likely to report an improvement in pain had a history of past incontinence sling (p=0.03). Posttreatment complications included: constipation (8%), worsening urinary retention (2%), and urinary tract infection (4%).

conclusionsBotox combined with soft tissue myofascial release physical therapy under anesthesia can be effective in treating women with chronic pelvic pain secondary to MFPP.

Indexed as

Acetylcholine Release InhibitorsAdultAgedAnesthesia, GeneralBotulinum Toxins, Type AChronic PainCombined Modality TherapyFemaleHumansInjections, IntramuscularMiddle AgedMusculoskeletal ManipulationsMyofascial Pain SyndromesPain MeasurementPelvic PainRetrospective StudiesAcetylcholine Release InhibitorsBotulinum Toxins, Type ABotoxMyofascial painPelvic painTherapy

Identifiers

PMID28261683
PMCPMC5330376
OpenAlexW2590962070

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.