Evidence map›Paper›PMID 28261570›Full record

ArticleFrontiers in cellular and infection microbiology2017

Human Salivary Protein Histatin 5 Has Potent Bactericidal Activity against ESKAPE Pathogens.

Han Du, Sumant Puri, Andrew McCall, Hannah L Norris, Thomas Russo, Mira Edgerton

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Exploring the Healing Powers of Histatins: From Oral Health to Therapeutics.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Antimicrobial peptides: from discovery to developmental applications.Applied and environmental microbiology · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Extracellular vesicles ofCurrent research in microbial sciences · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Han DuDepartment of Oral Biology, School of Dental Medicine, University at Buffalo Buffalo, NY, USA.
Sumant PuriDepartment of Oral Biology, School of Dental Medicine, University at Buffalo Buffalo, NY, USA.
Andrew McCallDepartment of Oral Biology, School of Dental Medicine, University at Buffalo Buffalo, NY, USA.
Hannah L NorrisDepartment of Oral Biology, School of Dental Medicine, University at Buffalo Buffalo, NY, USA.
Thomas RussoVeterans Administration Western New York Healthcare SystemBuffalo, NY, USA; The Department of Medicine, University at BuffaloBuffalo, NY, USA; Department of Microbiology and Immunology, University at BuffaloBuffalo, NY, USA; The Witebsky Center for Microbial Pathogenesis, University at BuffaloBuffalo, NY, USA.
Mira EdgertonDepartment of Oral Biology, School of Dental Medicine, University at Buffalo Buffalo, NY, USA.
University at Buffalo, State University of New York · USVA Western New York Healthcare System · US

Funding

Supplements to Support Candida DNA Microarray FacilitiesR01DE010641 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EDGERTON, MIRA · 2000 to 2019
$6.7M
Advanced Training in Oral BiologyT32DE023526 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Stefan Hans-Klaus Ruhl · 2013 to 2026
$3.7M
Regulation of Candida albicans Pathogenesis by the Signaling Mucin Msb2R01DE022720 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CULLEN, PAUL JAMES, EDGERTON, MIRA · 2013 to 2017
$1.9M
NIDCR NIH HHS R01 DE010641NIDCR NIH HHS R01 DE022720NIDCR NIH HHS T32 DE023526
6 · The paper itself

Abstract

ESKAPE (

Indexed as

Anti-Bacterial AgentsBiofilmsGram-Negative BacteriaGram-Positive BacteriaHistatinsHumansMicrobial ViabilityAnti-Bacterial AgentsHistatinsHTN3 protein, humanantimicrobial peptidebactericidal activityCandida albicansESKAPEHistatin 5

Identifiers

PMID28261570
PMCPMC5309243
OpenAlexW2588993345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.