Evidence map›Paper›PMID 28261566›Full record

ArticleFrontiers in cellular and infection microbiology2017

Efflux Pump Overexpression Contributes to Tigecycline Heteroresistance in

Yi Chen, Daxing Hu, Qijing Zhang, Xiao-Ping Liao, Ya-Hong Liu, Jian Sun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Emergence of plasmid-borneMicrobiology spectrum · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. The tigecycline resistance mechanisms in Gram-negative bacilli.Frontiers in cellular and infection microbiology · 2024
    Review
  14. Molecular mechanisms of tigecycline-resistance amongFrontiers in cellular and infection microbiology · 2024
    Review
  15. Article
  16. Review
  17. Antimicrobial Resistance ofPathogens (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Article
  20. Relationships between Efflux Pumps and Emergence of Heteroresistance: A Comprehensive Study on the Current Findings.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yi ChenNational Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural UniversityGuangzhou, China; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural UniversityGuangzhou, China.
Daxing HuNational Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural UniversityGuangzhou, China; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural UniversityGuangzhou, China.
Qijing ZhangDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State University Ames, IA, USA.
Xiao-Ping LiaoNational Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural UniversityGuangzhou, China; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural UniversityGuangzhou, China.
Ya-Hong LiuNational Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural UniversityGuangzhou, China; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural UniversityGuangzhou, China.
Jian SunNational Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural UniversityGuangzhou, China; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural UniversityGuangzhou, China.
South China Agricultural University · CNIowa State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial heteroresistance has been identified in several combinations of bacteria and antibiotics, and it complicated the therapeutic strategies. Tigecycline is being used as one of the optimal options for the treatment of infections caused by multidrug-resistant

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsMinocyclineMutationPlasmidsSalmonella InfectionsSalmonella typhimuriumSequence Analysis, DNATigecyclineAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsMinocyclineTigecyclineefflux pumpheteroresistanceplasmidSalmonella enterica serovar Typhimuriumtigecycline

Identifiers

PMID28261566
PMCPMC5313504
OpenAlexW2588569080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.