Evidence map›Paper›PMID 28261444›Full record

ArticleToxicology research2017

Prediction of the effect of formulation on the toxicity of chemicals.

Pritesh Mistry, Daniel Neagu, Antonio Sanchez-Ruiz, Paul R Trundle, Jonathan D Vessey, John Paul Gosling

Open access · hybridAbstract read
In one paragraph

Article in Toxicology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Pritesh MistryArtificial Intelligence Research Group , Faculty of Engineering and Informatics , University of Bradford , Bradford , UK.
Daniel NeaguArtificial Intelligence Research Group , Faculty of Engineering and Informatics , University of Bradford , Bradford , UK.
Antonio Sanchez-RuizLhasa Limited , Granary Wharf House , 2 Canal Wharf , Holbeck , Leeds , LS11 9PS , UK . Email: jonathan.vessey@lhasalimited.org.
Paul R TrundleArtificial Intelligence Research Group , Faculty of Engineering and Informatics , University of Bradford , Bradford , UK.
Jonathan D VesseyLhasa Limited , Granary Wharf House , 2 Canal Wharf , Holbeck , Leeds , LS11 9PS , UK . Email: jonathan.vessey@lhasalimited.org.
John Paul GoslingSchool of Mathematics , University of Leeds , Leeds , UK.
University of Bradford · GBUniversity of Leeds · GBUniversity of Pittsburgh at Bradford · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two approaches for the prediction of which of two vehicles will result in lower toxicity for anticancer agents are presented. Machine-learning models are developed using decision tree, random forest and partial least squares methodologies and statistical evidence is presented to demonstrate that they represent valid models. Separately, a clustering method is presented that allows the ordering of vehicles by the toxicity they show for chemically-related compounds.

Identifiers

PMID28261444
PMCPMC5310521
OpenAlexW2546466010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.