Evidence map›Paper›PMID 28261316›Full record

ArticleNutrition & metabolism2017

Defective lipid metabolism associated with mutation in

Jun Ling, Christopher Brey, Megan Schilling, Farah Lateef, Zenaida P Lopez-Dee, Kristopher Fernandes, Kavita Thiruchelvam, Yi Wang, Kshitij Chandel, Kai Rau and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nutrition & metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Jun LingDepartment of Basic Sciences, Geisinger Commonwealth School of Medicine, 525 Pine Street, Scranton, PA 18509 USA.
Christopher BreyScience Department, Marywood University, Scranton, PA 18509 USA.
Megan SchillingMolecular, Cellular and Integrative Biosciences Huck Institute of the Life Sciences, The Pennsylvania State University, University Park, PA 16802 USA.
Farah LateefLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Zenaida P Lopez-DeeDepartment of Basic Sciences, Geisinger Commonwealth School of Medicine, 525 Pine Street, Scranton, PA 18509 USA.
Kristopher FernandesLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Kavita ThiruchelvamLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Yi WangLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Kshitij ChandelLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Kai RauLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Ranjit ParharDepartment of Cell Biology-Cardiovascular unit, KFSH&RC, Riyadh, Saudi Arabia.
Futwan Al-MohannaDepartment of Cell Biology-Cardiovascular unit, KFSH&RC, Riyadh, Saudi Arabia.
Randy GauglerLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Sarwar HashmiLaboratory of Developmental Biology, Center for Vector Biology, Rutgers University, 180, Jones Avenue, New Brunswick, NJ 08901 USA.
Rutgers, The State University of New Jersey · USCommonwealth Medical College · USKing Faisal Specialist Hospital & Research Centre · SAMarywood University · USPennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary salts are important factors in metabolic disorders. They are vital components of enzymes, vitamins, hormones, and signal transduction that act synergistically to regulate lipid metabolism. Our previous studies have identified that Krüppel-like factor -3 (KLF-3) is an essential regulator of lipid metabolism. However, it is not known if KLF-2 also regulates lipid metabolism and whether KLF-2 and -3 mediate the effects of dietary salts on lipid metabolism.

methodsIn this study, we used

results

conclusionDietary Ca

Indexed as

Caenorhabditis elegans (C. elegans)Dietary saltKLF-2KLF-3KLF mutantKrüppel like factor (KLF)Lipid metabolism

Identifiers

PMID28261316
PMCPMC5331652
OpenAlexW2591753874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.