Evidence map›Paper›PMID 28261309›Full record

ArticleIranian journal of pharmaceutical research : IJPR2016

Preparation and Characterization of Three Tilmicosin-loaded Lipid Nanoparticles: Physicochemical Properties and

Alwan Al-Qushawi, Ali Rassouli, Fatemeh Atyabi, Seyed Mostafa Peighambari, Mehdi Esfandyari-Manesh, Gholam Reza Shams, Azam Yazdani

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
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  7. Review
  8. Article
  9. Article
  10. Preparation, Statistical Optimization andIranian journal of pharmaceutical research : IJPR · 2020
    Article
  11. Theranostics Aspects of Various Nanoparticles in Veterinary Medicine.International journal of molecular sciences · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alwan Al-QushawiDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Ali RassouliDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Fatemeh AtyabiDepartment of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Mostafa PeighambariDepartment of Avian Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Mehdi Esfandyari-ManeshNanotechnology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Gholam Reza ShamsDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Azam YazdaniDepartment of Avian Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
University of Tehran · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tilmicosin (TLM) is an important antibiotic in veterinary medicine with low bioavailability and safety. This study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization, and antibacterial activity of three TLM-loaded lipid nanoparticles (TLM-LNPs) including solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), and lipid-core nanocapsules (LNCs). Physicochemical parameters such as particle size-mean diameter, polydispersity index, zeta potential, drug encapsulation efficiency (EE), loading capacity, and morphology of the formulations were evaluated and the effects of various cryoprotectants during lyophilization and storage for 8 weeks were also studied. The profiles of TLM release and the antibacterial activities of these TLM-LNPs suspensions (against

Indexed as

Antibacterial activityLipid nanoparticlesMannitolStabilityTilmicosin

Identifiers

PMID28261309
PMCPMC5316245
OpenAlexW2561865027

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.