Evidence map›Paper›PMID 28261280›Full record

ArticleArchives of medical science : AMS2017

Effect of irradiation on DNA synthesis,

Jerzy Nowak, Bogna Świątek-Kościelna, Ewelina M Kałużna, Jolanta Rembowska, Agnieszka Dzikiewicz-Krawczyk, Mariola Zawada, Danuta Januszkiewicz-Lewandowska

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jerzy NowakDepartment of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Bogna Świątek-KościelnaDepartment of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Ewelina M KałużnaDepartment of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Jolanta RembowskaDepartment of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Agnieszka Dzikiewicz-KrawczykDepartment of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Mariola ZawadaDepartment of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Danuta Januszkiewicz-LewandowskaDepartment of Molecular Pathology, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland; Department of Paediatric Oncology, Haematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland.
Institute of Human Genetics · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe MATERIAL AND

methodsImmortalized B-lymphocytes with

resultsIncreasing the irradiation dose resulted in gradual decrease of

conclusionsThe results obtained indicate that homozygous c.657-661del mutation affects cell sensitivity to irradiation. Moreover, homozygous variant is associated with disturbance in the activation of cell cycle checkpoints and with defects in DNA repair. In turn, heterozygous c.657-661del, p.R215W and p.I171V mutations do not substantially alter the radiosensitivity.

Indexed as

DNA damagegenetic instabilityNBNnibrinradiosensitivity

Identifiers

PMID28261280
PMCPMC5332466
OpenAlexW2588589789

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.