Evidence map›Paper›PMID 28261115›Full record

ArticleFrontiers in psychiatry2017

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia.

Dasiel O Borroto-Escuela, Alexander O Tarakanov, Karl Bechter, Kjell Fuxe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Genetic overlap between treatment-resistant schizophrenia and smoking initiation.The international journal of neuropsychopharmacology · 2026
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  5. Article
  6. Extracellular vesicle approach to major psychiatric disorders.European archives of psychiatry and clinical neuroscience · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 4 countries.

Dasiel O Borroto-EscuelaDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Biomolecular Science, Section of Physiology, Campus Scientifico Enrico Mattei, University of Urbino, Urbino, Italy; Observatorio Cubano de Neurociencias, Grupo Bohío-Estudio, Yaguajay, Cuba.
Alexander O TarakanovRussian Academy of Sciences, St. Petersburg Institute for Informatics and Automation , Saint Petersburg , Russia.
Karl BechterClinic for Psychiatry and Psychotherapy II, Ulm University, Bezirkskrankenhaus Günzburg , Günzburg , Germany.
Kjell FuxeDepartment of Neuroscience, Karolinska Institutet , Stockholm , Sweden.
Cuban Neuroscience Center · CUKarolinska Institutet · SESt. Petersburg Institute for Informatics and Automation · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mild neuroinflammation hypothesis of schizophrenia was introduced by Bechter in 2001. It has been hypothesized that a hypofunction of glutamatergic signaling

Indexed as

chemokine receptorscytokine receptorsheteroreceptor complexesneuroinflamationNMDARreceptor–receptor interactionsschizophreniavolume transmission

Identifiers

PMID28261115
PMCPMC5309215
OpenAlexW2588305320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.