Evidence map›Paper›PMID 28260989›Full record

ArticleInternational journal of medical sciences2017

Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms with Hepatocellular Carcinoma in Taiwan.

Wayne Shih-Wei Huang, Hung-Yu Lin, Chao-Bin Yeh, Li-You Chen, Ying-Erh Chou, Shun-Fa Yang, Yu-Fan Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wayne Shih-Wei HuangDepartment of Surgery, Show Chwan Memorial Hospital, Changhua, Taiwan.
Hung-Yu LinInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Ophthalmology, Show Chwan Memorial Hospital, Changhua, Taiwan; Department of Optometry, Yuan Pei University, Hsinchu, Taiwan.
Chao-Bin YehSchool of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Emergency Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
Li-You ChenDepartment of Anatomy, Faculty of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Ying-Erh ChouSchool of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.
Yu-Fan LiuDepartment of Biomedical Sciences, College of Medicine Sciences and Technology, Chung Shan Medical University, Taichung, Taiwan; Division of Allergy, Department of Pediatrics, Chung-Shan Medical University Hospital, Taichung, Taiwan.
Chung Shan Medical University · TWChung Shan Medical University Hospital · TWChang Bing Show Chwan Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the second leading cause of cancer death in Taiwan. Multiple risk factors, such as chronic hepatitis B or C virus infection, carcinogen exposure, cirrhosis, and various single-nucleotide polymorphisms (SNPs), are considered to contribute to hepatocarcinogenesis. Chitinase-3-like protein 1 (CHI3L1), a biomarker implicated in inflammation and tissue remodeling, plays a promoting role in angiogenesis, antiapoptosis, and cell proliferation. This study investigated the role of

Indexed as

AgedCarcinoma, HepatocellularChitinase-3-Like Protein 1FemaleGenetic Predisposition to DiseaseHumansLiver NeoplasmsMaleMiddle AgedPolymorphism, Single NucleotideReal-Time Polymerase Chain ReactionTaiwanCHI3L1 protein, humanChitinase-3-Like Protein 1CHI3L1Hepatocellular carcinomaSingle nucleotide polymorphism

Identifiers

PMID28260989
PMCPMC5332842
OpenAlexW2590335270

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.