ArticleTherapeutics and clinical risk management2017
Increased risk of endotracheal intubation and heart failure following acute myocardial infarction in patients with urolithiasis: a nationwide population-based study.
Article in Therapeutics and clinical risk management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Association between kidney stones and major adverse cardiovascular events: a population-based analysis.Urolithiasis · 2026Article
- Paraventricular Nucleus P2X7 Receptors Aggravate Acute Myocardial Infarction Injury via ROS-Induced Vasopressin-V1b Activation in Rats.Neuroscience bulletin · 2021Article
- Incidence of Cellulitis Following Acupuncture Treatments in Taiwan.International journal of environmental research and public health · 2019Article
- Depression Negatively Impacts Survival of Patients with Metastatic Prostate Cancer.International journal of environmental research and public health · 2018Article
- Increased risk of pernicious anemia following scabies: a nationwide population-based matched-cohort study.Therapeutics and clinical risk management · 2017Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUrolithiasis is a common urinary tract disease worldwide. It has been connected to systemic diseases, including hypertension, diabetes mellitus, metabolic syndrome, and cardiovascular disease. In the current study, we aimed to evaluate the relationship between urolithiasis and the complications of acute myocardial infarction (AMI). MATERIALS AND
methodsData were obtained from the Longitudinal Health Insurance Database 2005 of the National Health Insurance Research Database. All AMI cases, both those who were hospitalized and those who were treated in the emergency department, were identified using the
resultsA total of 37,052 patients with urinary calculi and 148,209 control subjects were enrolled in this study. The average follow-up period was 9.51 years. The risk of AMI was higher among patients with urolithiasis (adjusted hazard ratio [aHR] 1.07, 95% confidence interval [95% CI] 1.03-1.13). We detected a significant association between urolithiasis and intubation (aHR 1.53, 95% CI 1.36-1.73), intensive care unit treatment (aHR 1.22, 95% CI 1.13-1.32), heart failure (aHR 1.59, 95% CI 1.42-1.78), shock (aHR 1.53, 95% CI 1.32-1.77), and arrhythmias (aHR 1.18, 95% CI 1.06-1.33). Furthermore, certain medical treatments for urolithiasis were found to be related to myocardial infarction (MI). Nonsteroidal anti-inflammatory drugs (NSAIDs) were significantly associated with a high risk of AMI. In contrast, allopurinol, thiazide diuretic, potassium-sparing diuretics, and α-blockers have negative association with AMI.
conclusionUrolithiasis had a significantly increased risk of endotracheal intubation and heart failure following AMI. In addition, urolithiasis was also associated with a high risk of intensive care unit treatment, shock, and arrhythmias after AMI. Medical treatments for urolithiasis may decrease the risk of MI, except the use of NSAIDs.
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