Evidence map›Paper›PMID 28260839›Full record

ArticleSynlett : accounts and rapid communications in synthetic organic chemistry2016

Metal-catalyzed Decarboxylative Fluoroalkylation Reactions.

Brett R Ambler, Ming-Hsiu Yang, Ryan A Altman

Abstract read
In one paragraph

Article in Synlett : accounts and rapid communications in synthetic organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Copper-Catalyzed Trifluoromethylation of Alkyl Bromides.Journal of the American Chemical Society · 2019
    Article
  7. Catalytic One-Step Deoxytrifluoromethylation of Alcohols.The Journal of organic chemistry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brett R AmblerDepartment of Medicinal Chemistry, The University of Kansas, Lawrence, Kansas 66045, United States.
Ming-Hsiu YangDepartment of Medicinal Chemistry, The University of Kansas, Lawrence, Kansas 66045, United States.
Ryan A AltmanDepartment of Medicinal Chemistry, The University of Kansas, Lawrence, Kansas 66045, United States.

Funding

TRAINING GRANT IN DYNAMIC ASPECTS OF CHEMICAL BIOLOGYT32GM008545 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LAMB, AUDREY L · 1994 to 2019
$4.9M
NIGMS NIH HHS T32 GM008545
6 · The paper itself

Abstract

Metal-catalyzed decarboxylative fluoroalkylation reactions enable the conversion of simple O-based substrates into biologically relevant fluorinated analogs. Herein, we present decarboxylative methods that facilitate the synthesis of trifluoromethyl- and difluoroketone-containing products. We highlight key mechanistic aspects that are critical for efficient catalysis, and that inspired our thinking while developing the reactions.

Indexed as

CatalysisCopperDecarboxylationDifluoroketoneFluorinePalladiumTrifluoromethylation

Identifiers

PMID28260839
PMCPMC5330304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.