Evidence map›Paper›PMID 28260819›Full record

ArticleTetrahedron letters2016

Synthesis of Site-Specifically

Adam R Offenbacher, Hui Zhu, Judith P Klinman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tetrahedron letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Biochemistry · 2023
    Article
  4. Article
  5. Journal of the American Chemical Society · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Adam R OffenbacherDepartment of Chemistry, University of California, Berkeley, Berkeley, California, 94720; Quantitative Institutes of Biosciences, University of California, Berkeley, Berkeley, California, 94720.
Hui ZhuDepartment of Chemistry, University of California, Berkeley, Berkeley, California, 94720; Quantitative Institutes of Biosciences, University of California, Berkeley, Berkeley, California, 94720.
Judith P KlinmanDepartment of Chemistry, University of California, Berkeley, Berkeley, California, 94720; Quantitative Institutes of Biosciences, University of California, Berkeley, Berkeley, California, 94720; Department of Molecular and Cellular Biology, University of California, Berkeley, Berkeley, California, 94720.
University of California, Berkeley · US

Funding

Looking in New Directions for Origins and Cryptic Mechanisms of Enzyme CatalysisR35GM118117 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI KLINMAN, JUDITH P · 2016 to 2025
$7.5M
Linking Dynamical Contributions to Biological Hydrogen Tunneling in LipoxygenasesF32GM113432 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI OFFENBACHER, ADAM · 2015 to 2016
$120k
NIGMS NIH HHS F32 GM113432NIGMS NIH HHS R35 GM118117
6 · The paper itself

Abstract

Soybean lipoxygenase-1 (SLO-1) catalyzes the C-H abstraction from the reactive carbon (C-11) in linoleic acid as the first and rate-determining step in the formation of alkylhydroperoxides. While previous labeling strategies have focused on deuterium labeling to ascertain the primary and secondary kinetic isotope effects for this reaction, there is an emerging interest and need for selectively enriched

Indexed as

hydrogen tunnelinglinoleic acidlipoxygenaseSecondary isotope effects

Identifiers

PMID28260819
PMCPMC5333924
OpenAlexW2511016030

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.